The global burden of disease in 1990: summary results, sensitivity analysis and future directions.
The global burden of disease in 1990: summary results, sensitivity analysis and future directions.
复制标题
DOI：
--
复制
发表时间：
1994
影响因子：
11.1
通讯作者：
C. J. L. Murray;A. D. Lopez;D. Jamison
中科院分区：
文献类型：
--
作者：
C. J. L. Murray;A. D. Lopez;D. Jamison
评估健康干预措施成本效益的基本要求是对特定疾病和伤害造成的健康不良（过早死亡和残疾）的程度进行全面评估。 1990 年，制定了一项新指标，即伤残调整生命年 (DALY)，用于评估按年龄、性别和地区划分的 100 多种原因造成的疾病和伤害负担。伤残调整生命年概念提供了一种综合、全面的方法来捕获 1990 年由于新的疾病和伤害病例而在一生中平均造成的全部健康不良状况。它在许多方面不同于以前的全球和区域健康状况评估尝试，后者通常在范围上不太全面、不太详细，并且仅限于少数原因。本文按原因、年龄、性别和地区总结了 1990 年 DALY 估计值。那些负责决定卫生部门优先事项的人员第一次能够获得一套分类的估计数据，这些估计数据除了促进成本效益分析外，还可用于监测一百多种疾病的全球和区域卫生进展。该论文还展示了估计如何取决于计算中涉及的参数的特定值。
A basic requirement for evaluating the cost-effectiveness of health interventions is a comprehensive assessment of the amount of ill health (premature death and disability) attributable to specific diseases and injuries. A new indicator, the number of disability-adjusted life years (DALYs), was developed to assess the burden of disease and injury in 1990 for over 100 causes by age, sex and region. The DALY concept provides an integrative, comprehensive methodology to capture the entire amount of ill health which will, on average, be incurred during one's lifetime because of new cases of disease and injury in 1990. It differs in many respects from previous attempts at global and regional health situation assessment which have typically been much less comprehensive in scope, less detailed, and limited to a handful of causes. This paper summarizes the DALY estimates for 1990 by cause, age, sex and region. For the first time, those responsible for deciding priorities in the health sector have access to a disaggregated set of estimates which, in addition to facilitating cost-effectiveness analysis, can be used to monitor global and regional health progress for over a hundred conditions. The paper also shows how the estimates depend on particular values of the parameters involved in the calculation.