STRUCTURE OF NANAOMYCIN-E, A NEW NANAOMYCIN
STRUCTURE OF NANAOMYCIN-E, A NEW NANAOMYCIN
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DOI：
10.7164/antibiotics.32.442
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发表时间：
1979-01-01
影响因子：
3.3
通讯作者：
OMURA, S
中科院分区：
文献类型：
--
作者：
KASAI, M;SHIRAHATA, K;OMURA, S
从玫瑰链霉菌发酵液中分离得到一种新的成分纳诺霉素E。纳米霉素E是纳米霉素A的环氧衍生物，在酸性水溶液中用亚硫酸钠处理后转化为纳米霉素A和4a-表纳米霉素B。在碱性条件下，4A-epi-纳米霉素B定量转化为纳米霉素A。
A new component, nanaomycin E, was isolated from the culture broth of Streptomyces rosa var. notoensis, which produces nanomycins A, B, C and D. Nanomycin E was an epoxy derivative of nanomycin A and was converted into nanaomycin A and 4a-epi-nanomycin B by treatment with sodium hydrosulfite in an acidic aqueous solution. 4a-epi-Nanaomycin B was quantitatively converted into nanaomycin A under alkaline conditions.