Temporal specificity in Pavlovian-to-instrumental transfer.
Temporal specificity in Pavlovian-to-instrumental transfer.
复制标题
巴甫洛夫到乐器传输的时间特异性。
DOI：
10.1101/lm.046383.117
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
DellaValle,RebeccaB
中科院分区：
文献类型：
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作者：
Matell,MatthewS;DellaValle,RebeccaB
当有机体进行操作反应时，呈现先前训练的巴甫洛夫条件刺激可以调节反应速率，这种现象称为巴甫洛夫到仪器的转移。尽管众所周知，巴甫洛夫偶发事件会产生根据预测结果的到来而在时间上组织的条件行为，但很少有工作研究巴甫洛夫工具转移过程中响应的时间动态。我们在巴甫洛夫任务中使用固定时间 60 秒、固定时间 120 秒或随机时间 60 秒的时间表训练大鼠，发现条件刺激的呈现以反映这些先前建立的时间预期的方式增强了操作反应。此外，这种时间特异性符合标量属性，如其他形式的间隔计时行为所示。令人惊讶的是，只有当条件刺激是视觉提示时才会出现这种效应，而当它是听觉提示时则不会。这些数据表明，巴甫洛夫线索触发的动机过程不是静态的，而是随着时间上特定的奖励预期的强度而波动。
Presentation of a previously trained Pavlovian conditioned stimulus while an organism is engaged in operant responding can moderate the rate of responding, a phenomenon known as Pavlovian-to-instrumental transfer. Although it is well known that Pavlovian contingencies will generate conditioned behavior that is temporally organized with respect to the arrival of the predicted outcome, little work has examined the temporal dynamics of responding during Pavlovian-instrumental transfer. We trained rats using a fixed time 60-sec, fixed time 120-sec, or random time 60-sec schedule in an appetitive Pavlovian task, and found that presentation of the conditioned stimulus potentiated operant responding in a manner that reflected these previously established temporal expectancies. Further, this temporal specificity conformed to the scalar property as seen with other forms of interval timing behavior. Surprisingly, this effect was only seen when the conditioned stimulus was a visual cue, but not when it was an auditory cue. These data suggest that the motivational processes triggered by Pavlovian cues are not static, but fluctuate in strength as a function of temporally specific expectations of reward.