Methodological and structural challenges in pallative care research: how have we fared in the last decades?
Methodological and structural challenges in pallative care research: how have we fared in the last decades?
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DOI：
10.1177/0269216306072620
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发表时间：
2006-01-01
影响因子：
4.4
通讯作者：
Loge, Jon Havard
中科院分区：
文献类型：
--
作者：
Kaasa, Stein;Hjermstad, Marianne Jensen;Loge, Jon Havard
姑息治疗人群的异质性代表了对研究方法的挑战，包括研究设计、知情同意（和一般的伦理问题），症状和体征的评估和分类，以及临床中的实际问题。本报告的目的是通过调查和文献综述的方式描述和检查欧洲姑息治疗研究的现状。只有一个欧洲国家，英国，2005年，通过支持性和姑息治疗协作组织（SUPAC），采取了一项全国性举措，激励和促进姑息治疗研究。有几个欧洲的姑息治疗研究小组达到临界规模，几个国家没有姑息治疗的学术椅子，也没有明显的趋势，椅子正在出现一般。姑息治疗研究几乎没有公共资金。姑息治疗研究人员需要在“开放市场”上竞争或依赖私人基金会。在EAPC研究论坛上发表的摘要数量稳步增加，从2000年的200篇增加到2006年的480篇。文献回顾表明，大多数出版物是调查和描述性/观察性研究，很少有随机对照研究发表。可能需要进行更大规模的多中心研究，为了进行这种研究，需要国家和国际结构，包括临界规模以上的研究，并具有多学科背景，包括基础科学家和临床医生。
The heterogeneity of the palliative care population represents challenges to research methodology, including study design, informed consent (and ethical issues in general), assessment and classification of symptoms and signs, as well as practical issues in the clinic.The aim of this report is to describe and examine the status of palliative care research in Europe by means of a survey and a literature review.Only one European country, the UK, has taken a national initiative to stimulate and promote palliative care research through the supportive and palliative care collaboratives (SUPAC) in 2005. There are few European research groups in palliative care reaching a critical size, several countries do not have academic chairs in palliative care, and there is no clear trend that chairs are emerging in general. There is little public funding for palliative care research. Palliative care researchers need to compete on the 'open market' or rely on private foundations.There has been a steady increase in the number of abstracts for presentation at the EAPC Research Forums, from 200 in 2000, to 480 in 2006. The literature review indicated that the majority of publications are surveys and descriptive/observational studies, and few randomised, controlled, studies were published.In conclusion, the quantity of research seems to be steadily increasing. There may be a need for larger multi-centre studies, and in order to perform such studies, national and international structures, encompassing research above the critical size, with a multi-disciplinary background including both basic scientists and clinicians is required.