Effects of earplugs and eye masks on nocturnal sleep, melatonin and cortisol in a simulated intensive care unit environment
Effects of earplugs and eye masks on nocturnal sleep, melatonin and cortisol in a simulated intensive care unit environment
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DOI：
10.1186/cc8965
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发表时间：
2010-01-01
期刊：
影响因子：
15.1
通讯作者：
Zhang, You-hua
中科院分区：
文献类型：
--
作者：
Hu, Rong-fang;Jiang, Xiao-ying;Zhang, You-hua
导言：环境刺激，特别是噪音和光线，被认为会扰乱重症监护病房(ICU)患者的睡眠。本研究旨在确定ICU噪声和光线以及耳塞和眼罩在这些条件下对健康受试者的生理和心理影响。方法：14名受试者在适应、基线、暴露于记录的ICU噪声和光线(NL)和NL加使用耳塞和眼罩(NLEE)四种条件下进行多导睡眠监测。分析尿液中褪黑激素和皮质醇水平。结果：暴露在模拟ICU噪声和光线中的受试者睡眠质量较差，睡眠时间较浅，快速眼动(REM)潜伏期较长，REM睡眠较少(P<；0.05)。夜间褪黑激素(P=0.007)和皮质醇分泌水平(P=0.004)因病情不同而有显著差异，但焦虑水平无显著差异(P=0.06)。使用耳塞和眼罩可延长快速眼动时间、缩短快速眼动潜伏期、减少觉醒时间(P=0.002)和升高褪黑素水平(P=0.05)。结论：耳塞和眼罩可促进暴露于模拟ICU噪声和光线下的健康受试者的睡眠和激素平衡，使其在ICU患者中的推广是合理的。
Introduction: Environmental stimulus, especially noise and light, is thought to disrupt sleep in patients in the intensive care unit (ICU). This study aimed to determine the physiological and psychological effects of ICU noise and light, and of earplugs and eye masks, used in these conditions in healthy subjects.Methods: Fourteen subjects underwent polysomnography under four conditions: adaptation, baseline, exposure to recorded ICU noise and light (NL), and NL plus use of earplugs and eye masks (NLEE). Urine was analyzed for melatonin and cortisol levels. Subjects rated their perceived sleep quality, anxiety levels and perception of environmental stimuli.Results: Subjects had poorer perceived sleep quality, more light sleep, longer rapid eye movement (REM) latency, less REM sleep when exposed to simulated ICU noise and light (P < 0.05). Nocturnal melatonin (P = 0.007) and cortisol secretion levels (P = 0.004) differed significantly by condition but anxiety levels did not (P = 0.06). Use of earplugs and eye masks resulted in more REM time, shorter REM latency, less arousal (P < 0.05) and elevated melatonin levels (P = 0.002).Conclusions: Earplugs and eye masks promote sleep and hormone balance in healthy subjects exposed to simulated ICU noise and light, making their promotion in ICU patients reasonable.