Serum levels of protein S100B predict intracranial lesions in mild head injury
Serum levels of protein S100B predict intracranial lesions in mild head injury
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DOI：
10.1016/j.clinbiochem.2012.01.006
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发表时间：
2012-04-01
影响因子：
2.8
通讯作者：
Lippi, Giuseppe
中科院分区：
文献类型：
--
作者：
Cervellin, Gianfranco;Benatti, Mario;Lippi, Giuseppe
目的：本研究的目的是评估是否血清S100 B水平在急诊入院可以用来省略不必要的计算机断层扫描（CT）在轻微的头部损伤（MHI）的患者（MHI）设计和方法：60例连续的患者与最近的MHI被纳入本研究。结果：60例颅脑损伤患者中，20例CT扫描阳性，其中20例CT扫描阳性。CT阳性患者的S100 B蛋白值显著高于CT阴性患者（1.35 μ g/L对0.48 μ g/L; p
Objectives: This study was aimed to assess whether serum S100B levels at emergency department admission can be used to omit unnecessary computed tomography (CT) in patients with minor head injury (MHI).Design and methods: Sixty consecutive patients with recent MHI were included in this study. Serum S100B measurement and CT scanning were performed in all patients within 3 h from head injury.Results: A positive CT scan was present in 20 out of 60 subjects. Significantly higher values of protein S100B were found in CT positive than in CT negative patients (1.35 versus 0.48 mu g/L; p