A reusable perfusion supporting tissue-mimicking material for ultrasound hyperthermia phantoms.
A reusable perfusion supporting tissue-mimicking material for ultrasound hyperthermia phantoms.
复制标题
一种用于超声热疗模型的可重复使用的灌注支持组织模拟材料。
DOI：
10.1118/1.596517
复制
发表时间：
1990
期刊：
影响因子：
3.8
通讯作者：
Frank,GR
中科院分区：
文献类型：
--
作者：
Chin,RB;Madsen,EL;Zagzebski,JA;Jadvar,H;Wu,XK;Frank,GR
报道了一种新的超声和外科组织模拟材料。该材料非常适合在用于测试超声热疗系统或相关预测模型的体模中使用。受控的对流热传递效应，在一定程度上模仿组织中的灌注热传递，可以在具有适当的流体源和汇的材料中建立。该材料由紧密堆积的琼脂球组成，直径为0.3-3.6 mm。球之间的间隙填充有10%正丙醇溶液。与固体凝胶型组织模拟材料相比，该材料具有两个实际优势。第一个优点是，它允许在通过灌注流体的快速循环进行加热测试之后使热疗体模快速返回到热平衡。第二个优点是材料是“液体”形式。它可以很容易地从任何几何形状的幻影容器中虹吸进出，用于不同的目的，而不会改变其物理特性。测量方法和材料的热力学性质和测量结果的报告。测量的物理参数包括强度衰减和吸收系数、超声速度、热导率、比热容和质量密度。还报道了由该材料制成的热疗体模中的温度测量结果。
A new ultrasonically and thermodynamically tissue‐mimicking material is reported. The material is well suited for use in phantoms for testing ultrasound hyperthermia systems or related predictive models. Controlled convective heat transfer effects, mimicking to some extent perfusive heat transfer in tissues, can be instituted in the material with appropriate fluid sources and sinks. The material consists of closely packed agar spheres varying in diameters from 0.3–3.6 mm. The interstitial space between spheres is filled with 10%n‐propanol solution. The material has two practical advantages over the solid‐gel‐type tissue‐mimicking materials. The first advantage is that it allows rapid return of a hyperthermia phantom to thermal equilibrium following a heating test by rapid circulation of the perfusion fluid. The second advantage is that the material is in a “liquid” form. It can be easily siphoned in and out of phantom containers of any geometric shape for different purposes without change in its physical properties. Methods for measuring ultrasonic and thermodynamic properties of the material and the results of the measurements are reported. The physical parameters measured are the intensity attenuation and absorption coefficients, the ultrasonic speed, the thermal conductivity, specific‐heat capacity and the mass density. Temperature measurements in a hyperthermia phantom made of the material are also reported.