Seasonal allergies and suicidality: results from the National Comorbidity Survey Replication

Seasonal allergies and suicidality: results from the National Comorbidity Survey Replication
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DOI:
10.1111/j.1600-0447.2009.01518.x
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发表时间:
2010-08-01
影响因子:
6.7
通讯作者:
Goodwin, R. D.
Goodwin, R. D.
中科院分区:
医学1区
文献类型:
--
作者:
Messias, E.;Clarke, D. E.;Goodwin, R. D.

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目的:研究表明过敏与自杀之间存在关联,并且还描述了自杀的季节性。我们假设季节性过敏史与自杀意念和企图之间存在关联。方法:数据来自全国合并症调查复制,这是居住在美国的成年人的全国代表性样本(n = 5692)。使用逻辑回归模型计算调整后的比值比 (OR),控制以下因素:年龄、性别、种族、吸烟、哮喘和抑郁。结果:经过加权和调整后,发现季节性过敏史与自杀意念史之间存在统计学上显着的正相关关系 [调整后的 OR = 1.27 (1.01-1.58)]。我们发现季节性过敏史与自杀未遂史之间没有关联[调整后 OR = 1.17 (0.89-1.52)]。结论:基于人群的样本研究结果支持过敏与自杀意念之间的假设关系。
Objective:Studies have shown an association between allergies and suicidality, and a seasonality of suicide has also been described. We hypothesize an association between history of seasonal allergies and suicide ideation and attempt.Method:Data came from the National Comorbidity Survey Replication, a nationally representative sample (n = 5692) of adults living in the US. Logistic regression models were used to calculate adjusted odds ratios (OR) controlling for the following: age, sex, race, smoking, asthma and depression.Results:After weighting and adjustment, a positive and statistically significant association was found between history of seasonal allergies and history of suicidal ideation [adjusted OR = 1.27 (1.01-1.58)]. We found no association between history of seasonal allergies and history of suicide attempts [adjusted OR = 1.17 (0.89-1.52)].Conclusion:Findings from a population-based sample support the hypothesized relationship between allergies and suicidal ideation.