Risk of another basal cell carcinoma developing after treatment of a basal cell carcinoma.
Risk of another basal cell carcinoma developing after treatment of a basal cell carcinoma.
复制标题
基底细胞癌治疗后发生另一种基底细胞癌的风险。
DOI：
10.1097/00006534-199407000-00068
复制
发表时间：
1994
影响因子：
13.8
通讯作者：
M. Abadir
中科院分区：
文献类型：
--
作者：
A. Marghoob;A. Kopf;R. Bart;L. Sanfilippo;M. Silverman;P. Lee;E. Levy;K. Vossaert;S. Yadav;M. Abadir
背景
有一个新的基底细胞癌（BCC）发展的风险增加的人谁有BCC。
目的
本研究试图确定这种风险增加的程度。
方法
回顾了260例经组织学证实为基底细胞癌的白色患者的病历，以了解新基底细胞癌的发生情况。将这些患者新发基底细胞癌的5年累积发病率（改良生命表法）与美国一般白色人群的5年发病率进行比较。
结果
在260例患者中，137例在平均38.3个月内发生了新的BCC，5年累积发生一个或多个新的BCC的发生率为45.2%。在5年的时间间隔内，研究人群中发生新BCC的年度风险仍然很高。在美国一般白色人群中，最大5年发病率计算为5%（p < 0.005，卡方检验）。
结论
有基底细胞癌病史的患者需要终身随访，因为新的基底细胞癌发生的可能性很高。
BACKGROUND
There is an increased risk of new basal cell carcinomas (BCCs) developing in a person who has had a BCC.
OBJECTIVE
This study attempts to define the magnitude of this increased risk.
METHODS
The charts of 260 white patients with a histologically proven BCC were reviewed for the occurrence of new BCCs. The cumulative 5-year incidence (modified life-table method) for new BCCs developing in these patients was compared with the 5-year incidence in the general white population of the United States.
RESULTS
Of the 260 patients, new BCCs developed in 137 within an average of 38.3 months, a 5-year cumulative rate of one or more new BCCs of 45.2%. The yearly risk for new BCCs developing in the study population remained high during the 5-year interval. In the general white population of the United States, the maximal 5-year incidence was calculated to be 5% (p < 0.005, chi-square test).
CONCLUSION
Patients with a history of BCC require life-long follow-up because of the high probability of new BCCs developing.