The Childhood Asthma Management Program (CAMP): Contributions to the Understanding of Therapy and the Natural History of Childhood Asthma.

The Childhood Asthma Management Program (CAMP): Contributions to the Understanding of Therapy and the Natural History of Childhood Asthma.
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DOI:
10.1007/s13665-012-0026-9
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发表时间:
2012-12
期刊:
Current respiratory care reports
影响因子:
--
通讯作者:
the Childhood Asthma Management Program Research Group
the Childhood Asthma Management Program Research Group
中科院分区:
其他
文献类型:
--
作者:
Covar RA;Fuhlbrigge AL;Williams P;Kelly HW;the Childhood Asthma Management Program Research Group

文献摘要

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儿童哮喘管理计划(CAMP)已经持续存在了近二十年,这使其成为最大的随机,安慰剂对照临床试验,并对轻度至中度哮喘儿童进行了长期随访。因此,其从基线、积极治疗和治疗后的累积数据已被证明是一种宝贵的资源,不仅用于评估儿童长期吸入皮质类固醇治疗的疗效和安全性,而且用于发现儿童哮喘的许多其他方面,包括遗传学和生物标志物。
The Childhood Asthma Management Program (CAMP) has been in continuous existence for almost two decades, which makes it the largest randomized, placebo-controlled clinical trial with extended follow-up for children with mild to moderate asthma. As such, its cumulative data from baseline, active treatment, and post-treatment have proved to be an invaluable resource for not only assessing the efficacy and safety of long-term inhaled corticosteroid therapy in childhood, but for discovery of many other aspects of childhood asthma, including genetics and biomarkers.