Fluoride effectiveness in high caries risk and medically complex Veterans.
Fluoride effectiveness in high caries risk and medically complex Veterans.
复制标题
氟化物对高龋齿风险和病情复杂的退伍军人有效。
DOI：
10.1111/cdoe.12121
复制
发表时间：
2014
影响因子：
2.3
通讯作者：
Jones,JudithA
中科院分区：
文献类型：
--
作者：
Jurasic,MMarianne;Gibson,Gretchen;Wehler,CarolynJ;Nunn,Martha;Orner,MichelleB;Nunez,Elizabeth;O'Toole,TerryG;Jones,JudithA
背景全球疾病负担研究显示，从 1990 年到 2010 年，因龋齿而致残的年数增加了 34.5%。随着 7600 万婴儿潮一代的老龄化，龋齿将继续对老年人构成重大挑战。目的在临床环境中测试处方或专业应用的氟化物在预防新牙齿修复体方面的有效性，在该环境中，患者的医疗状况较一般人群受到损害，并且牙齿受损程度更高。方法A回顾性队列研究，使用退伍军人事务部内的多个电子数据库。使用倾向评分来调整适应症的混杂因素，逻辑回归对结果进行建模，并包括所有预期的协变量。结果研究样本包括 140 114 名高龋齿风险退伍军人，平均每名患者有 3.4 种身体合并症、1.2 种精神合并症和 11 个药物组。接受临床氟化物治疗的患者在随访期间需要修复的几率降低了 17-20%。结论在护理之前或期间提供的处方自行施用或专业施用的氟化物显着降低了高龋齿风险和健康状况不佳的退伍军人进行新修复的可能性。
BackgroundThe Global Burden of Disease Study showed there was a 34.5% increase in years lived with disability due to dental caries from 1990 to 2010. With the aging of 76 million baby boomers, dental caries will continue to pose a significant challenge for older adults.ObjectiveTest the effectiveness of prescription or professionally applied fluoride in the prevention of new dental restorations in a clinical setting where patients are medically compromised and more dentally impaired than the general population.MethodsA retrospective cohort study, using multiple electronic databases within the Department of Veterans Affairs. Propensity scores were used to adjust for confounding by indication and logistic regression modeled the outcome and included all expected covariates.ResultsThe study sample included 140 114 high caries risk Veterans with a mean of 3.4 physical comorbidities, 1.2 mental comorbidities, and 11 medication groups per patient. Patients who received clinical fluoride treatments had 17–20% decreased odds of requiring a restoration during the follow‐up period.ConclusionsPrescription self‐applied or professionally applied fluoride provided either before or during an episode of care significantly reduced the likelihood of new restorations in high caries risk and medically compromised Veterans.