Preparation of Benzothiazoles and Heterocyclic Spiro Compounds Through Cu-catalyzed S-S Bond Cleavage and C-S Bond Formation
Preparation of Benzothiazoles and Heterocyclic Spiro Compounds Through Cu-catalyzed S-S Bond Cleavage and C-S Bond Formation
复制标题
Cu催化S-S键断裂和C-S键形成制备苯并噻唑和杂环螺化合物
DOI：
10.1002/ajoc.202200211
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发表时间：
2022
影响因子：
2.7
通讯作者：
Yasuhiro Uozumi
中科院分区：
文献类型：
--
作者：
Keisuke Minami;Maki Minakawa;Yasuhiro Uozumi
2，2 '-二硫代双苯胺与各种醛在乙酸铜催化剂存在下，在空气中无任何添加剂的条件下反应，得到相应的苯并噻唑。当环烷基甲醛在类似条件下反应时，生成苯并噻唑和杂环螺环化合物。在Cu 0Ac催化剂存在下在开瓶条件下成功地进行了克级制备。
The reaction of 2,2'‐dithiobis(benzenamine)s with various aldehydes in the presence of CuOAc catalyst under air without any additives afforded the corresponding benzothiazoles. When cycloalkylcarbaldehydes were reacted under similar conditions, benzothiazoles and heterocyclic spiro compounds were produced. Gram‐scale preparation was successfully performed in the presence of CuOAc catalyst under open‐flask conditions.