The right hemisphere's contribution to emotional word processing in currently depressed, remitted depressed, and never-depressed individuals
The right hemisphere's contribution to emotional word processing in currently depressed, remitted depressed, and never-depressed individuals
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DOI：
10.1016/j.jneuroling.2006.06.004
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发表时间：
2007-03-01
影响因子：
2
通讯作者：
Minatrea, April Diane
中科院分区：
文献类型：
--
作者：
Atchley, Ruth Ann;Stringer, Ryan;Minatrea, April Diane
为了研究单极抑郁症如何影响大脑半球对情绪刺激的处理，对抑郁、缓解抑郁和从不抑郁的参与者进行了评估。语义刺激选择他们的效价（积极与消极）和他们的能力，产生情感唤起（高与低）。在完成一个结构化的临床访谈，以确定抑郁症的经验，参与者被要求作出价的判断，横向提出的情感词。研究结果表明，右半球（RH）是特别敏感的情感语义内容的情绪刺激，此外，两个有趣的高阶相互作用中观察到的RH。首先，在Atchley等人[2003.词义中情绪内容处理的半球不对称性：当前和过去抑郁的影响。Brain and Language，84，105-119]，经历过抑郁症的个体（包括目前抑郁和缓解抑郁的群体）在处理消极词汇时表现出优势，而从未抑郁的个体在处理积极词汇时表现出优势。此外，在RH中，情感唤醒与刺激效价（但不是诊断组）相互作用，使所有参与者表现出优势时，分类高度唤起负面信息，而积极的话，低唤起刺激更准确地确定。这些结果进行了讨论的背景下，抑郁症的认知模型，并在方面的一般模型的半球专业化的情绪处理。(c)2006爱思唯尔有限公司保留所有权利。
To examine how unipolar depression influences hemispheric processing of emotional stimuli, words with clear affective content were assessed by depressed, remitted depressed, and never depressed participants. Semantic stimuli were selected for both their valence (positive vs. negative) and for their ability to engender affective arousal (high vs. low). After completing a structured clinical interview to determine depression experience, participants were asked to make valence judgements for laterally presented emotional words. Study results suggest that the right hemisphere (RH) is particularly sensitive to the affective semantic content of emotional stimuli, furthermore, two interesting higher order interactions were observed in the RH. First, in a replication of recent findings by Atchley et al. [2003. Hemispheric asymmetry in the processing of emotional content in word meanings: The effect of current and past depression. Brain and Language, 84, 105-119], individuals who have experienced depression (both currently depressed and remitted depressed groups) show an advantage when processing negatively valent words, while the never depressed individuals show an advantage for positive words. Also in the RH, affective arousal interacted with stimulus valence (but not diagnostic group), such that all participants exhibited an advantage when categorizing highly arousing negative information, while for positive words the low arousing stimuli were identified more accurately. These results are discussed in the context of models of depressive cognition and in regards to general models of hemispheric specialization for emotion processing. (c) 2006 Elsevier Ltd. All rights reserved.