Effectiveness of Pretreatment in Decreasing Adverse Events Associated with Pamidronate in Children and Adolescents

Effectiveness of Pretreatment in Decreasing Adverse Events Associated with Pamidronate in Children and Adolescents
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预处理在减少儿童和青少年帕米膦酸钠不良事件方面的有效性

DOI:
10.1592/phco.24.2.195.33143
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发表时间:
2004
期刊:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
影响因子:
--
通讯作者:
J. Mahan
J. Mahan
中科院分区:
--
文献类型:
--
作者:
R. F. Robinson;M. Nahata;J. Hayes;D. Batisky;C. Bates;J. Mahan

文献摘要

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研究的目标。评估布洛芬或对乙酰氨基酚预处理与不预处理相比,在减少儿童和青少年接受第一和第二系列帕米膦酸盐治疗的不良事件方面的有效性;并比较布洛芬和对乙酰氨基酚在预防帕米膦酸钠输注相关不良事件方面的有效性。
Study Objectives. To assess the effectiveness of pretreatment with ibuprofen or acetaminophen compared with no pretreatment in decreasing adverse events in children and adolescents receiving the first and second series of pamidronate therapy; and to compare the effectiveness of ibuprofen versus acetaminophen for prevention of adverse events associated with pamidronate infusion.