Frontal-parietal activation differences observed before the execution of remembered saccades: an event-related potentials study
Frontal-parietal activation differences observed before the execution of remembered saccades: an event-related potentials study
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DOI：
10.1016/s0926-6410(01)00037-4
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发表时间：
2001-08-01
期刊：
影响因子：
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通讯作者：
Papageorgiou, C
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文献类型：
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作者：
Evdokimidis, I;Smyrnis, N;Papageorgiou, C
健康受试者在一种记忆 (MEM) 和两种记忆（延迟任务延迟，DEL 和修改延迟，M-DEL）中进行眼跳运动，同时我们从 25 个电极部位记录头皮事件相关电位 (ERP)。在 MEM 任务中，受试者被要求将视觉目标的位置延迟 1-6 秒保留在记忆中，然后在发出 go 信号时执行记住的扫视。在 DEL 任务中，目标保持打开状态直到移动完成，而在 M-DEL 任务中，在延迟期间可见的目标与 go 信号同步消失。与两个延迟任务相比，在 MEM 任务中观察到反应延迟减少和运动失调百分比增加。与顶叶电极位点相比，中央额叶电极位点的 ERP 活动增加仅对延迟期早期（500-1000 毫秒）的 MEM 任务显着。在眼跳开始之前的一段时间内，观察到所有任务的顶叶活动均增加。此外，与仅在记忆任务中的顶叶区域相比，额叶的活动较小，因此表明在早期延迟期间观察到的先前活动模式几乎逆转。仅在 MEM 任务中观察到的额叶和顶叶区域的这种特定激活模式需要进一步研究，重点关注参与工作记忆处理的大脑区域激活的时间模式。 (C) 2001 Elsevier Science B.V. 保留所有权利。
Healthy subjects performed saccadic eye movements in one memory (MEM) and two (delay tasks delay, DEL and modified delay, M-DEL) while we recorded scalp event-related potentials (ERPs) from 25 electrode sites. In the MEM task the subjects were instructed to retain in memory the location of a visual target for a delay of 1-6 s and then perform a remembered saccade at the go signal. In the DEL task, the target remained on until movement completion and in the M-DEL task the target, that was visible during the delay period, disappeared synchronously with the go signal. A reduction in response latency and an increase in the percentage of dysmetric movements were observed fur the MEM task compared to the two delay tasks. An increased ERP activity at the central-frontal electrode sites compared to the parietal sites was significant only for the MEM task early on during the delay period (500-1000 ms). During the period preceding the onset of the saccade, a parietal increase of activity was observed for all tasks. Furthermore the activity was smaller for the frontal compared to the parietal areas only for the memory task thus indicating a near reversal of the previous pattern of activity observed during the early delay period. This specific activation pattern of frontal and parietal areas, observed for the MEM task only, requires further investigation focusing on the temporal pattern of activation of large brain areas involved in working memory processing. (C) 2001 Elsevier Science B.V. All rights reserved.