Expectations and placebo response: A laboratory investigation into the role of somatic focus
Expectations and placebo response: A laboratory investigation into the role of somatic focus
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DOI：
10.1007/s10865-005-9040-5
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发表时间：
2006-04-01
影响因子：
3.1
通讯作者：
Kosbab, K
中科院分区：
文献类型：
--
作者：
Geers, AL;Helfer, SG;Kosbab, K
理论上认为，预期是安慰剂效应的一个重要因果决定因素。然而，安慰剂预期并不总是产生安慰剂效果。在一项实验室研究中，我们测试了这样一种假设，即一个人的躯体注意力水平会缓和安慰剂预期对安慰剂反应的影响。我们还对参与者是否被告知安慰剂是一种药物，可能是药物或安慰剂，还是安慰剂有所不同。结果显示，那些认为自己在服用药物(即无条件期望)的人，当他们密切关注自己的症状时，报告了更多的安慰剂症状。被告知他们可能会或可能不会接受药物治疗的个体(即有条件的期望)与对照组参与者没有区别，无论他们对自己的症状有多密切的关注。这一发现对安慰剂效应的预期模型以及比较临床试验和临床实践中个人预期类型的实际研究具有理论意义。
It has been theorized that expectations are an important causal determinant of the placebo effect. Placebo expectations, however, do not always yield placebo effects. In a laboratory study, we tested the hypothesis that one's level of somatic focus moderates the effect of placebo expectations on placebo responding. We also varied whether participants were told the placebo was a drug, could either be a drug or placebo, or was a placebo. The results revealed that individuals who thought they were taking a drug (i.e., unconditional expectations) reported more placebo symptoms when they closely focused on their symptoms. Individuals told they may or may not be receiving a drug (i.e., conditional expectations) did not differ from control participants regardless of how closely they attended to their symptoms. The findings have theoretical implications for expectancy models of the placebo effect as well as for practical research comparing the type of expectations held by individuals in clinical trials and clinical practice.