Ancient DNA analysis of human neolithic remains found in northeastern Siberia
Ancient DNA analysis of human neolithic remains found in northeastern Siberia
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DOI：
10.1002/ajpa.20257
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发表时间：
2005-04-01
影响因子：
2.8
通讯作者：
Ludes, B
中科院分区：
文献类型：
--
作者：
Ricaut, FX;Fedoseeva, A;Ludes, B
我们成功地从雅库特东北部(东西伯利亚)出土的新石器时代骨架(年代为3600+/-60年前)的骨骼样本中提取了DNA。通过常染色体STR(短串联重复序列)和线粒体DNA(MtDNA)控制区高变区I(HV1)的测序来分析古代DNA。将STR图谱、线粒体单倍型和所确定的单倍群与现代欧亚人和美洲原住民的STR图谱进行比较。结果表明，这具古老的骨骼与东西伯利亚人/亚洲人和美洲原住民都有亲和力。
We successfully extracted DNA from a bone sample of a Neolithic skeleton (dated 3,600 +/- 60 years BP) excavated in northeastern Yakutia (east Siberia). Ancient DNA was analyzed by autosomal STRs (short tandem repeats) and by sequencing of the hypervariable region I (HV1) of the mitochondrial DNA (mtDNA) control region. The STR profile, the mitochondrial haplotype, and the haplogroup determined were compared with those of modern Eurasian and Native American populations. The results showed the affinity of this ancient skeleton with both east Siberian/Asian and Native American populations.