A depth-sensing technique on 3D-printed compensator for total body irradiation patient measurement and treatment planning.
A depth-sensing technique on 3D-printed compensator for total body irradiation patient measurement and treatment planning.
复制标题
3D 打印补偿器的深度传感技术，用于全身照射患者测量和治疗计划。
DOI：
10.1118/1.4964452
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发表时间：
2016
期刊：
影响因子：
3.8
通讯作者：
Suh,Tae-Suk
中科院分区：
文献类型：
--
作者：
Lee,Min-Young;Han,Bin;Jenkins,Cesare;Xing,Lei;Suh,Tae-Suk
目的全身照射技术的目的是将均匀的辐射剂量照射到患者的整个身体体积。由于患者的厚度不同，很难在全身产生如此均匀的剂量分布。在许多技术中，补偿器被用来调整输送到患者不同部位的剂量。本研究旨在开发和验证一种将深度传感摄像头和3D打印技术用于脑外伤治疗规划和补偿器制造的创新方法。方法使用集成了深度传感摄像头和运动跟踪传感器的平板电脑扫描放置在脑外伤治疗亭中的随机™体模，以点云格式检测和存储3D表面。通过将提取的身体厚度测量结果与来自计算机断层扫描(CT)图像的相应测量结果进行比较，来评估检测表面的准确性。测量不同部位体模的厚度、源表面距离和离轴距离，为脑外伤治疗方案的制定提供依据。计算了详细的补偿器设计，以实现整个体模中均匀的剂量分布。利用3D打印机、硅胶模塑和蜡钨粉混合物制作了补偿器。在活体剂量测量中，使用光刺激发光探测器进行了测量。结果体模的扫描时间约为30 S，每个体模的厚度测量相对于CT的平均误差为0.48±0.2 7 cm。3D打印补偿器的平均制造误差为0.16±0.15 mm。在端到端测试的活体测量中，总剂量差在5%以内。结论使用配备深度相机的平板电脑和3D打印机来规划和制造用于脑外伤治疗的补偿器的技术被证明是足够准确的，可以考虑进一步研究。
PurposeThe purpose of total body irradiation (TBI) techniques is to deliver a uniform radiation dose to the entire volume of a patient's body. Due to variations in the thickness of the patient, it is difficult to produce such a uniform dose distribution throughout the body. In many techniques, a compensator is used to adjust the dose delivered to various sections of the patient. The current study aims to develop and validate an innovative method of using depth‐sensing cameras and 3D printing techniques for TBI treatment planning and compensator fabrication.MethodsA tablet with an integrated depth‐sensing camera and motion tracking sensors was used to scan a RANDO™ phantom positioned in a TBI treatment booth to detect and store the 3D surface in a point cloud format. The accuracy of the detected surface was evaluated by comparing extracted body thickness measurements with corresponding measurements from computed tomography (CT) scan images. The thickness, source to surface distance, and off‐axis distance of the phantom at different body section were measured for TBI treatment planning. A detailed compensator design was calculated to achieve a uniform dose distribution throughout the phantom. The compensator was fabricated using a 3D printer, silicone molding, and a mixture of wax and tungsten powder.In vivodosimetry measurements were performed using optically stimulated luminescent detectors.ResultsThe scan of the phantom took approximately 30 s. The mean error for thickness measurements at each section of phantom relative to CT was 0.48 ± 0.27 cm. The average fabrication error for the 3D‐printed compensator was 0.16 ± 0.15 mm.In vivomeasurements for an end‐to‐end test showed that overall dose differences were within 5%.ConclusionsA technique for planning and fabricating a compensator for TBI treatment using a depth camera equipped tablet and a 3D printer was demonstrated to be sufficiently accurate to be considered for further investigation.