Giant acquired acral fibrokeratoma: A case report

Giant acquired acral fibrokeratoma: A case report
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巨大获得性肢端纤维角化瘤:一例报告

DOI:
10.4081/dr.2019.8215
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发表时间:
2019
影响因子:
1.1
通讯作者:
Hend Al
Hend Al
中科院分区:
--
文献类型:
--
作者:
Hend Al

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获得性肢端纤维角化瘤(AAF)是一种罕见的良性纤维性肿瘤。它的尺寸通常很小(即0.5厘米)。然而,很少有巨大病变(即>1厘米)的病例被报道。1例17岁沙特男性患者,在沙特阿拉伯阿赛尔地区阿赛尔中心医院皮肤科门诊就诊,右中趾背侧长出一无痛性圆形皮肤色外生结节,直径1.7厘米。肿瘤被外科手术切除了。组织病理学检查发现一个巨大的多倍体病变,由大量角化过度、棘皮病、厚胶原束核心和垂直定向的真皮小血管组成。诊断为巨大AAF。手术切除后没有复发的证据。AAF是一种罕见的良性皮肤肿瘤,应与其他类似的皮肤病变相鉴别。手术切除是治疗的第一线。
Acquired acral fibrokeratoma (AAF) is a rare benign fibrous tumor. Its size is usually small (i.e., <0.5 cm). However, few cases with giant lesions (i.e., >1 cm) have been reported. A 17-year-old Saudi male presented to the Dermatology Outpatient Clinic of Aseer Central Hospital, Aseer Region, Saudi Arabia, with a painless rounded skin-colored exophytic nodule arising from the dorsal surface of the right middle toe, 1.7 cm in diameter. The tumor was surgically excised. Histopathology examination revealed a giant polyploid lesion, composed of massive hyperkeratosis, acanthosis, a core of thick collagen bundles and vertically oriented small dermal blood vessels. The diagnosis was giant AAF. There was no evidence of recurrence after surgical excision. AAF is a rare benign skin tumor which should be differentiated from other similar skin lesions. Surgical excision is the first line for treatment.