Worldwide Epidemiology of Salmonella Serovars in Animal-Based Foods: a Meta-analysis
Worldwide Epidemiology of Salmonella Serovars in Animal-Based Foods: a Meta-analysis
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DOI：
10.1128/aem.00591-19
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发表时间：
2019-07-01
影响因子：
4.4
通讯作者：
Conte-Junior, Carlos A.
中科院分区：
文献类型：
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作者：
Ferrari, Rafaela G.;Rosario, Denes K. A.;Conte-Junior, Carlos A.
沙门氏菌是最重要的食源性病原体之一，也是世界范围内导致人类死亡的第三大疾病。动物是这种病原体的主要来源，动物性食品是向人类传播的主要途径。因此，了解沙门氏菌血清型的全球流行病学是控制和监测这种细菌的关键。在此背景下，本研究旨在评估五大洲（非洲、美洲[北美和拉丁美洲]、亚洲、欧洲和大洋洲）动物性食品（牛肉、猪肉、家禽和海鲜）中肠道沙门氏菌血清型的流行率和多样性。荟萃分析包括化学计量学评估（分层聚类分析和主成分分析），以确定主要的流行病学结果，包括每个矩阵中沙门氏菌血清型的患病率和多样性。关于血清型分布，S。鼠伤寒杆菌呈世界性分布，在所有四个评估的基质和大陆中均有报告;家禽在肠道菌血清型向人类传播中继续发挥核心作用，Anatum和Weltevreden分别是牛肉和海鲜中最常见的。此外，我们建议仔细监测某些血清型，如Derby、Agona、Infantis和肯塔基州。最后，鉴于最常报告的血清型和哪些基质构成该病原体传播的主要媒介的科学数据，可以改进控制程序，并可以实施特定的干预措施，以降低该病原体到达人类的风险。重要性沙门氏菌病由沙门氏菌属引起。是食物传播疾病中的第三大死因。这种病原体通常在家畜和野生动物中传播，感染的症状表现为急性发热、恶心、腹痛和腹泻。动物是沙门氏菌的主要来源，动物性食品是沙门氏菌向人类传播的主要途径。因此，从这些来源收集的数据可能有助于未来的全球干预措施，以有效控制和监测沙门氏菌沿着食物链。鉴于此，我们研究的重要性在于确定沙门氏菌血清型在四种动物性食品基质（猪肉，家禽，牛肉和海鲜）中的流行程度，并评估每个基质作为该病原体对人类的主要来源的重要性。
Salmonella spp. are among the most important foodborne pathogens and the third leading cause of human death among diarrheal diseases worldwide. Animals are the primary source of this pathogen, and animal-based foods are the main transmission route to humans. Thus, understanding the global epidemiology of Salmonella serovars is key to controlling and monitoring this bacterium. In this context, this study aimed to evaluate the prevalence and diversity of Salmonella enterica serovars in animal-based foods (beef, pork, poultry, and seafood) throughout the five continents (Africa, the Americas [North and Latin America], Asia, Europe, and Oceania). The meta-analysis consisted of a chemometric assessment (hierarchical cluster analysis and principal component analysis) to identify the main epidemiological findings, including the prevalence and diversity of the Salmonella serovars in each matrix. Regarding the serovar distribution, S. Typhimurium presented a cosmopolitan distribution, reported in all four assessed matrices and continents; poultry continues to play a central role in the dissemination of the Enteritidis serovar to humans, and Anatum and Weltevreden were the most frequently found in beef and seafood, respectively. Additionally, we recommended careful monitoring of certain serovars, such as Derby, Agona, Infantis, and Kentucky. Finally, given the scientific data regarding the most frequently reported serovars and which matrices constitute the main vehicles for the transmission of this pathogen, control programs may be improved, and specific interventions may be implemented in an attempt to reduce the risk of this pathogen reaching humans.IMPORTANCE Salmonellosis is caused by Salmonella spp. and is the third leading cause of death among food-transmitted diseases. This pathogen is commonly disseminated in domestic and wild animals, and the infection's symptoms are characterized by acute fever, nausea, abdominal pain, and diarrhea. The animals are the primary source of salmonellae, and animal-based foods are the main transmission route to humans. Therefore, data collected from these sources could contribute to future global interventions for effective control and surveillance of Salmonella along the food chain. In light of this, the importance of our research is in identifying the prevalence of Salmonella serovars in four animal-based food matrices (pork, poultry, beef, and seafood) and to evaluate the importance that each matrix has as the primary source of this pathogen to humans.