MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test.

MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test.
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DOI:
10.1089/152091503322641060
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发表时间:
2003-01-01
影响因子:
5.4
通讯作者:
Bergman, Richard N
Bergman, Richard N
中科院分区:
医学3区
文献类型:
--
作者:
Boston, Ray C;Stefanovski, Darko;Bergman, Richard N

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Bergman最小模型能够估计葡萄糖/胰岛素动力学的两个关键指标:葡萄糖有效性和胰岛素敏感性。在本文中,我们描述MINMOD千年,最新的基于Windows的最小模型软件的版本。MINMOD Millennium的广泛beta测试表明,它是用户友好的,全自动的,快速,准确,可复制,可重复的,并且与过去的MINMOD版本高度一致。它有一个简单的界面,一个全面的帮助系统,一个输入文件编辑器,一个文件转换器,一个智能处理内核和一个文件导出器。它提供了葡萄糖和胰岛素的出版质量图表以及所有最小模型参数及其误差估计的表格。与MINMOD和其他一些最小模型程序的早期版本相比,Millennium提供了几乎每个受试者的胰岛素敏感性和葡萄糖有效性的确定估计值。
The Bergman Minimal Model enables estimation of two key indices of glucose/insulin dynamics: glucose effectiveness and insulin sensitivity. In this paper we describe MINMOD Millennium, the latest Windows-based version of minimal model software. Extensive beta testing of MINMOD Millennium has shown that it is user-friendly, fully automatic, fast, accurate, reproducible, repeatable, and highly concordant with past versions of MINMOD. It has a simple interface, a comprehensive help system, an input file editor, a file converter, an intelligent processing kernel, and a file exporter. It provides publication-quality charts of glucose and insulin and a table of all minimal model parameters and their error estimates. In contrast to earlier versions of MINMOD and some other minimal model programs, Millennium provides identified estimates of insulin sensitivity and glucose effectiveness for almost every subject.