Anti-inflammatory and analgesic activities of Edgeworthia chrysantha and its effective chemical constituents
Anti-inflammatory and analgesic activities of Edgeworthia chrysantha and its effective chemical constituents
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DOI：
10.1248/bpb.31.1761
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发表时间：
2008-09-01
影响因子：
2
通讯作者：
Zhang, Wei-Dong
中科院分区：
文献类型：
--
作者：
Hu, Xiao-Jia;Jin, Hui-Zi;Zhang, Wei-Dong
The barks and roots of Edgeworthia chrysantha LINDL., which have been used as the folk medicine "Zhushima" in southern China due to their detumescence and acesodyne effects, were investigated for their anti-inflammatory and analgesic activities using a xylene-induced ear edema assay in mice and Freund's complete adjuvant-induced paw edema as inflammation models, and the acetic acid-induced writhing test as an analgesic model. Fractions effective in terms of anti-inflammatory and analgesic activities were obtained from E. chrysantha. The chloroform-soluble fraction (CHF) showed significant anti-inflammatory (p
