COVID-19: an Immunopathological View
COVID-19: an Immunopathological View
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DOI：
10.1128/msphere.00344-20
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发表时间：
2020-03-01
期刊：
影响因子：
4.8
通讯作者：
Kadkhoda, Kamran
中科院分区：
文献类型：
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作者：
Kadkhoda, Kamran
自2019年12月出现以来，2019新型冠状病毒病（COVID-19）爆发仅用了几个月时间就被世界卫生组织（WHO）宣布为大流行病。这沿着疾病的高度传染性和相关的死亡率，要求特别关注潜在的（免疫）病理机制。后者将为病例管理和疫苗设计提供信息。解开这些机制可以帮助基础科学家，实验室医学从业者，临床医生，公共卫生从业者，资助机构和卫生保健政策制定者应对严重急性呼吸系统综合征冠状病毒2（SARS-CoV-2）大流行。
Since its emergence in December 2019, it took only a couple of months for an outbreak of the novel coronavirus disease 2019 (COVID-19) to be declared a pandemic by the World Health Organization (WHO). This along with the highly infectious nature of the disease and the associated mortality call for particular attention to the underlying (immuno)pathomechanism(s). The latter will inform case management and vaccine design. Unravelling these mechanisms can assist basic scientists, laboratory medicine practitioners, clinicians, public health practitioners, funding agencies, and health care policymakers in responding to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.