Bamboo charcoal inhibits growth of HeLa cells in vitro

Bamboo charcoal inhibits growth of HeLa cells in vitro
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DOI:
10.4012/dmj.23.633
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发表时间:
2004-12-01
影响因子:
2.5
通讯作者:
Takahashi, J
Takahashi, J
中科院分区:
工程技术3区
文献类型:
--
作者:
Teraoka, F;Hamada, Y;Takahashi, J

文献摘要

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这项工作的目的是研究用于牙科领域的竹炭粉的远红外光谱特性及其对癌细胞的影响。为了分析粉末的效果,使用 HeLa 和 WI-38 细胞,然后通过细胞粘附测定和 WST-1 测定进行评估。该粉末发射波长在4至16μm之间的远红外线。 WI-38细胞的增殖率在常规培养(对照组)和粉末培养(FIR组)之间没有显着差异。然而,孵育六天后,FIR组HeLa细胞的增殖率明显低于对照组。根据这项研究中发射的远红外线,竹炭粉被证明是一种有前途的预防癌症的牙科填充材料。
The purpose of this work was to investigate the far infrared spectral characteristics of bamboo charcoal powder and its effect on cancer cells for use in the dental field. To analyze the effects of the powder, HeLa and WI-38 cells were used and then assessed by cell adhesion assay and WST-1 assay. The powder emitted far infrared rays at wavelengths between 4 to 16 mu m. The multiplication rate of WI-38 cells showed no significant differences between the conventional culture (control group) and culture on the powder (FIR group). However, at six days after incubation, HeLa cells of FIR group had a significantly lower multiplication rate compared with the control group. Based on the far infrared rays emitted in this study, bamboo charcoal powder proved to be a promising dental filler material for cancer prevention.