ABSOLUTE-CONFIGURATION OF URINARY 2-HYDROXYBUTYRIC ACID IN PATIENTS WITH KETOSIS AND LACTIC-ACIDOSIS
ABSOLUTE-CONFIGURATION OF URINARY 2-HYDROXYBUTYRIC ACID IN PATIENTS WITH KETOSIS AND LACTIC-ACIDOSIS
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DOI：
10.1016/0009-8981(78)90168-7
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发表时间：
1978-01-01
影响因子：
5
通讯作者：
WADMAN, SK
中科院分区：
文献类型：
--
作者：
KAMERLING, JP;GERWIG, GJ;WADMAN, SK
本文用O-乙酰基（-）-薄荷酯衍生物的毛细管气相色谱法测定了乳酸血症和酮症患者尿中2-羟基丁酸和3-羟基丁酸的绝对构型。2-羟基丁酸酯具有L-构型，而3-羟基丁酸酯为D-构型。
The absolute configurations of urinary 2-hydroxybutyrate and 3-hydroxybutyrate were determined in patients with lactic acidemia and ketosis by capillary GLC of their O-acetylated (-)-menthyl ester derivatives. 2-Hydroxybutyrate had the L-configuration, whereas 3-hydroxybutyrate was in the D-configuration.