Excitation-contraction coupling and minor triadic proteins in low-frequency fatigue.
Excitation-contraction coupling and minor triadic proteins in low-frequency fatigue.
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DOI：
10.1097/jes.0b013e3181e3734d
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发表时间：
2010-07
影响因子：
5.7
通讯作者：
Balog EM
中科院分区：
文献类型：
--
作者：
Balog EM
低频疲劳(LFF)的特点是，与高激活频率相比，低激活频率下的力损失更大，恢复时间更长。最近的工作表明，钙诱导的兴奋-收缩偶联的解偶联是Lff的基础。在这里，描述了新的特征的三联体蛋白，并提出了可能的机制，通过它们可能有助于LFF。
Low-frequency fatigue (LFF) is characterized by a proportionally greater loss of force at low compared to high activation frequencies and a prolonged recovery. Recent work suggests a calcium-induced uncoupling of excitation-contraction coupling underlies LFF. Here newly characterized triadic proteins are described and possible mechanisms by which they may contribute to LFF are suggested.