Incorrect Use of the Student t Test in Randomized Trials of Bilateral Hip and Knee Arthroplasty Patients
Incorrect Use of the Student t Test in Randomized Trials of Bilateral Hip and Knee Arthroplasty Patients
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DOI：
10.1016/j.arth.2010.06.007
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发表时间：
2011-08-01
影响因子：
3.5
通讯作者：
Bhandari, Mohit
中科院分区：
文献类型：
--
作者：
Gandhi, Rajiv;Smith, Holly N.;Bhandari, Mohit
对研究结果的统计分析对研究结果的解释至关重要。通常混淆，2类型的t检验存在依赖或独立样本。我们回顾了随机对照试验，包括接受双侧全髋关节或全膝关节置换术的患者（依赖样本），使用t检验进行分析。我们的纳入标准导致了40项研究的审查，其中10个结合了单侧和双侧患者。在30项仅比较双侧患者纯样本的研究中，18项（60%）错误地使用了独立t检验。在10项混合样本研究中，8项（80%）使用了独立t检验。这种统计检验的不正确使用导致误导性结论的程度尚不确定;然而，我们的研究结果强调了关节置换术文献中统计检验的误用。
The statistical analysis of a study's results is critical to its interpretation. Often confused, 2 types of t tests exist for dependent or independent samples. We reviewed randomized controlled trials that included patients undergoing bilateral total hip or knee arthroplasty (dependent samples) that used the t test for analysis. Our inclusion criteria resulted in 40 studies for review, 10 of which combined both unilateral and bilateral patients. Of the 30 studies that compared a pure sample of only bilateral patients, 18 (60%) incorrectly used the independent t test. Of the 10 studies with mixed samples, 8 (80%) used the independent t test. The extent to which the incorrect use of this statistical test led to misleading conclusions is uncertain; however, our findings highlight the misuse of statistical tests in the arthroplasty literature.