Relationships of cervical, thoracic, and lumbar bone mineral density by quantitative CT
Relationships of cervical, thoracic, and lumbar bone mineral density by quantitative CT
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DOI：
10.1097/00004728-200101000-00027
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发表时间：
2001-01-01
影响因子：
1.3
通讯作者：
Whitley, PE
中科院分区：
文献类型：
--
作者：
Weishaupt, D;Schweitzer, ME;Whitley, PE
目的：本研究的目的是利用定量CT（QCT）比较颈椎、胸椎的椎体骨密度（BMD）。方法：对50例健康志愿者（女性25例，男性25例，平均年龄31.7岁）进行C2、C5、T12和L4椎体的QCT检查。在每个水平进行骨小梁BMD分析。女性和男性的平均BMD（mg/cm（3）羟基磷灰石钙）在C5时最高（BMD女性/男性341.6/300.6 mg/cm（3））和C2（297.2/269.6 mg/cm（3）），T12（193.1/184.9 mg/cm（3））和L4（186.2/180.1 mg/cm（3））最低。两种性别C2的BMD与C5、T12和L4的BMD差异有统计学意义（p < 0.0001）。C5的BMD与T12和L4的BMD也有显著性差异（p < 0.0001）。C5的BMD显示出显著的性别差异（p = 0.002）。相关系数显示，T12和L4骨密度在两种性别中均存在较强的相关性（女性r = 0.67;男性r = 0.90）。结论：在两种性别的非骨质疏松志愿者中，QCT测量的C2和C5骨小梁骨密度均显著高于T12和L4骨小梁骨密度。
Purpose: The purpose of this work was to compare, using quantitative CT (QCT), vertebral bone mineral density (BMD) in the cervical, thoracic. and lumbar spine in healthy volunteers.Method: QCT of the vertebral bodies of C2, C5, T12, and L4 was performed on 50 healthy volunteers (25 women, 25 men: mean age 31.7 years). Trabecular BMD analysis was performed at each level.Results: Mean BMDs (mg/cm(3) calcium hydroxyapatite) for women and men were highest at C5 (BMD women/men 341.6/300.6 mg/cm(3)) and C2 (297.2/269.6 mg/cm(3)) and lowest at T12 (193.1/184.9 mg/cm(3)) and L4 (186.2/180.1 mg/cm(3)). The BMD of C2 was statistically significantly different from that of C5, T12, and L4 (p < 0.0001) for both genders. Also, the BMD of C5 differed significantly from that of T12 and L4 (p < 0.0001). The BMD of C5 showed significant gender differences (p = 0.002). Correlation coefficient showed a strong correlation between the BMD of T12 and L4 for both genders (women, r = 0.67; men, r = 0.90).Conclusion: Trabecular BMD of C2 and C5 measured by QCT is significantly higher than trabecular BMD of T12 and L4 in nonosteoporotic volunteers of both genders.