Living donor liver transplantation for patients with HCC exceeding the Milan criteria: A proposal of expanded criteria

Living donor liver transplantation for patients with HCC exceeding the Milan criteria: A proposal of expanded criteria
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DOI:
10.1159/000106908
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发表时间:
2007-01-01
期刊:
影响因子:
2.3
通讯作者:
Uemoto, Shinji
Uemoto, Shinji
中科院分区:
医学3区
文献类型:
--
作者:
Takada, Yasutsugu;Ito, Takashi;Uemoto, Shinji

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背景资料:肝细胞癌(HCC)患者活体肝移植(LDLT)的最佳适应证尚未确定。本研究的目的是确定最佳标准,包括米兰标准(MC)之外的类别,仍然具有可预测的良好结果。患者和方法:1999年2月至2007年12月,136例HCC患者接受了LDLT。根据术前影像学检查,74例患者符合MC,62例不符合。结果:患者5年总生存率为70%。超过MC但出现以下症状的患者
Background: Optimal indications for living donor liver transplantation (LDLT) for patients with hepatocellular carcinoma (HCC) have yet not been established. The aim of the present study was to determine optimal criteria including categories outside the Milan criteria ( MC) and still with a predictably good outcome. Patients and Methods: Between February 1999 and December 2007, 136 patients with HCC underwent LDLT. Based on preoperative imaging studies, 74 patients met the MC and 62 did not. Results: Overall patient survival rate at 5 years was 70%. Patients who exceeded MC but presented with