Efficient oxidation of cycloalkanols by sodium nitrite with molecular oxygen in trifluoroacetic acid
Efficient oxidation of cycloalkanols by sodium nitrite with molecular oxygen in trifluoroacetic acid
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DOI：
10.1016/j.tetlet.2004.09.037
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发表时间：
2004-10-25
影响因子：
1.8
通讯作者：
Onomura, O
中科院分区：
文献类型：
--
作者：
Matsumura, Y;Yamamoto, Y;Onomura, O
在三氟乙酸中用亚硝酸钠氧化脂肪族环烷醇，以良好的产率得到α，ω-二羧酸。在氧气氛下使用1当量的亚硝酸钠从环己醇以定量产率获得己二酸，但是在氮气氛下氧化需要多于3当量的亚硝酸钠。氧化法适用于1-烷醇转化为相应的羧酸。(C)2004爱思唯尔有限公司保留所有权利。
Oxidation of aliphatic cycloalkanols by sodium nitrite in trifluoroacetic acid gave alpha,omega-dicarboxylic acids in good yields. Adipic acid was obtained in a quantitative yield from cyclohexanol using 1 equiv of sodium nitrite under oxygen atmosphere but the oxidation required more than 3 equiv of sodium nitrite under nitrogen atmosphere. The oxidation method was applicable to the conversion of 1-alkanols to the corresponding carboxylic acids. (C) 2004 Elsevier Ltd. All rights reserved.