Design and optimization of a hybrid distillation/melt crystallization process
Design and optimization of a hybrid distillation/melt crystallization process
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混合蒸馏/熔融结晶工艺的设计与优化
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
J. Strube
中科院分区：
文献类型：
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作者：
M. Franke;N. Nowotny;Eugene Ndocko Ndocko;A. Górak;J. Strube
混合蒸馏/熔融结晶工艺广泛用于异构体混合物的分离。混合分离过程的设计不是一个简单的任务，因为有几个结构和操作的自由度。在这篇文章中，提出了一个新的三步设计方法来解决上述挑战。在第一步中，工艺方案产生的启发式规则。在第二步中，通过使用快捷方法，优化生成的工艺方案的能耗。在第三步中，最有前途的替代品进行严格的优化，其总的年化成本，而由此产生的混合整数非线性规划（MINLP）问题的解决使用修改后的广义benders分解（GBD）算法，考虑到非凸性。这种设计方法的可行性证明了一个混合蒸馏/熔融结晶过程的设计分离的三元异构体混合物。© 2008美国化学工程师学会AIChE J，2008
Hybrid distillation/melt crystallization processes are widely used for the separation of isomer mixtures. The design of a hybrid separation processes is not a trivial task because of several structural and operational degrees of freedom. In this article, a new three-step design approach is proposed to address the above mentioned challenges. In the first step, process alternatives are generated by heuristic rules. In the second step, the generated process alternatives are optimized with respect to their energy consumption by using shortcut methods. In the third step, the most promising alternatives are rigorously optimized with respect to their total annualized costs, whereas the resulting mixed-integer nonlinear programming (MINLP) problem is solved using a modified generalized benders decomposition (GBD) algorithm to take the nonconvexities into account. The feasibility of this design approach is demonstrated by design of a hybrid distillation/melt crystallization process for separation of a ternary isomer mixture. © 2008 American Institute of Chemical Engineers AIChE J, 2008