ICU admission in patients infected with the human immunodeficiency virus - a multicentre survey
ICU admission in patients infected with the human immunodeficiency virus - a multicentre survey
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DOI：
10.1046/j.1365-2044.1999.00903.x
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发表时间：
1999-08-01
期刊：
影响因子：
10.7
通讯作者：
Soni, N
中科院分区：
文献类型：
--
作者：
Gill, JK;Greene, L;Soni, N
我们进行了一项回顾性研究，以评估人类免疫缺陷病毒（HIV）感染患者入住重症监护室的原因和随后的结局。英格兰南部的四家医院参加了该项目，所有医院都设有专门的艾滋病毒部门。1993年6月至1997年10月期间，在133个不同的场合收集了127例入住ICU的患者的数据。入院时的平均年龄为38岁（范围23-60岁）。94例患者（70.7%）在入院前被记录为HIV阳性，36例（27%）在入院期间首次被诊断为HIV阳性; 36.1%的患者因卡氏肺孢子虫肺炎入院。总体ICU死亡率为33%，住院死亡率为56%，随访结束时（1998年3月）的最终死亡率为72%。患有呼吸道艾滋病毒相关疾病或艾滋病毒无关疾病的患者生存率最高。与不良预后相关的因素包括既往患有AIDS定义疾病、CD 4细胞计数低于100 cells.ml（-1）和继发于败血症的入院。
We conducted a retrospective study to assess the reasons for admission to the intensive care unit, and subsequent outcome, in patients infected with the human immunodeficiency virus (HIV). Four hospitals in the south of England participated, all with specialist HIV units. Data were collected on 127 patients admitted to ICU on 133 separate occasions between June 1993 and October 1997. The mean age on admission was 38 years (range 23-60 years). Ninety-four patients (70.7%) were documented HIV-positive before admission and 36 (27%) were diagnosed HIV-positive positive for the first time during admission; 36.1% were admitted with Pneumocystis carinii pneumonia. Overall ICU mortality was 33%, in-hospital mortality was 56% and the eventual mortality at the end of follow-up (March 1998) was 72%. Survival was highest in those admitted with respiratory HIV-related disease or HIV-unrelated illness. Associations with poor outcome included a prior AIDS-defining illness, a CD4 cell count of less than 100 cells.ml(-1) and admission secondary to sepsis.