Vibrio vulnificus induces macrophage apoptosis in vitro and in vivo
Vibrio vulnificus induces macrophage apoptosis in vitro and in vivo
复制标题
DOI：
10.1128/iai.71.1.533-535.2003
复制
发表时间：
2003-01-01
影响因子：
3.1
通讯作者：
Susa, N
中科院分区：
文献类型：
--
作者：
Kashimoto, T;Ueno, S;Susa, N
在这项研究中，我们比较了创伤弧菌的临床和环境分离株对巨噬细胞在体外和体内的凋亡活动。临床分离株诱导巨噬细胞样细胞在体外和巨噬细胞在体内凋亡。这表明巨噬细胞凋亡可能是创伤弧菌临床毒力的重要因素。
In this study, we compared the apoptotic activities of clinical and environmental isolates of Vibrio vulnificus toward macrophages in vitro and in vivo. The clinical isolates induced apoptosis in macrophage-like cells in vitro and in macrophages in vivo. This suggests that macrophage apoptosis may be important for the clinical virulence of V. vulnificus.