Maladaptive Aortic Properties in Children After Palliation of Hypoplastic Left Heart Syndrome Assessed by Cardiovascular Magnetic Resonance Imaging
Maladaptive Aortic Properties in Children After Palliation of Hypoplastic Left Heart Syndrome Assessed by Cardiovascular Magnetic Resonance Imaging
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DOI：
10.1161/circulationaha.109.889733
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发表时间：
2010-09-14
期刊：
影响因子：
37.8
通讯作者：
Rickers, Carsten
中科院分区：
文献类型：
--
作者：
Voges, Inga;Jerosch-Herold, Michael;Rickers, Carsten
Background-The status of the reconstructed aorta in hypoplastic left heart syndrome is considered an important determinant of long-term prognosis. Therefore, we assessed the anatomy, elastic properties, and viability of the aorta and right ventricular function in patients with hypoplastic left heart syndrome by cardiovascular magnetic resonance imaging.Methods and Results-Cardiovascular magnetic resonance imaging was performed in 40 patients with hypoplastic left heart syndrome (age, 6.0 +/- 2.2 years) and 13 control subjects (age, 6.6 +/- 2.2 years). Aortic dimensions and distensibility were calculated at different locations of the aorta using gradient-echo cine imaging at 3.0 T. Additionally, pulse-wave velocity, right ventricular ejection fraction, and aortic late gadolinium enhancement for viability assessment were measured. Compared with control subjects, patients with hypoplastic left heart syndrome had increased axial diameters of the aortic root (36.0 +/- 5.5 versus 24.1 +/- 2.7 mm/m(2); P
