Prevalence and trends of symptomatic pelvic floor disorders in U.S. women.
Prevalence and trends of symptomatic pelvic floor disorders in U.S. women.
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DOI：
10.1097/aog.0000000000000057
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发表时间：
2014-01
影响因子：
7.2
通讯作者：
Markland AD
中科院分区：
文献类型：
--
作者：
Wu JM;Vaughan CP;Goode PS;Redden DT;Burgio KL;Richter HE;Markland AD
估计2005-2010年美国女性盆底疾病的患病率和趋势。我们使用了2005-2006年、2007-2008年和2009-2010年的国家健康和营养检查调查（NHANES）。共有7,924名非孕妇（年龄在20岁或以上）被分类为：尿失禁-中度至重度（尿失禁（UI）严重程度指数为3或更高，范围为0-12）；大便失禁-至少每月一次（固体、液体或粘液大便）；以及盆腔器官脱垂——看到或感觉到肿块。潜在危险因素包括年龄、种族和民族、胎次、教育程度、贫困收入比、体重指数（BMI）（<25、25 - 29、≥30 kg/m2）、合并症数和生殖因素。采用适当的抽样权重，加权卡方分析和多变量logistic回归模型的优势比（OR）和95%置信区间（95% CI）进行了报道。一种或多种盆底疾病的加权患病率为25.0% (95% CI 23.6, 26.3)，其中17.1% （95% CI 15.8, 18.4）为中重度尿失禁，9.4% （95% CI 8.6, 10.2）为大便失禁，2.9% （95% CI 2.5, 3.4）为脱垂。从2005年到2010年，任何一种疾病的患病率或所有疾病的合并患病率均无显著差异（p < 0.05）。在对潜在的混杂因素进行校正后，较高的BMI、较大的胎次和子宫切除术与一种或多种盆底疾病的较高几率相关。尽管2005-2010年盆底疾病的发生率没有变化，但这些疾病仍然很常见，四分之一的美国成年女性报告至少有一种疾病。
To estimate the prevalence and trends of these pelvic floor disorders in U.S. women from 2005–2010. We utilized the National Health and Nutritional Examination Survey (NHANES) from 2005–2006, 2007–2008, and 2009–2010. A total of 7,924 non-pregnant women (aged 20 years or older) were categorized as having: urinary incontinence – moderate to severe (3 or higher on a validated urinary incontinence (UI) severity index, range 0–12); fecal incontinence – at least monthly (solid, liquid, or mucus stool); and pelvic organ prolapse – seeing or feeling a bulge. Potential risk factors included age, race and ethnicity, parity, education, poverty income ratio, body mass index (BMI) (<25, 25–29, ≥30 kg/m2), co-morbidity count, and reproductive factors. Using appropriate sampling weights, weighted chi square analysis and multivariable logistic regression models with odds ratios (OR) and 95% confidence intervals (95% CI) were reported. The weighted prevalence rate of one or more pelvic floor disorder was 25.0% (95% CI 23.6, 26.3), including 17.1% (95% CI 15.8, 18.4) of women with moderate-to-severe urinary incontinence, 9.4% (95% CI 8.6, 10.2) with fecal incontinence, and 2.9% (95% CI 2.5, 3.4) with prolapse. From 2005 to 2010, no significant differences were found in the prevalence rates of any individual disorder or for all disorders combined (p>0.05). After adjusting for potential confounders, higher BMI, greater parity, and hysterectomy were associated with higher odds of one or more pelvic floor disorder. Although rates of pelvic floor disorders did not change from 2005–2010, these condition remain common with one quarter of adult U.S. women reporting at least one disorder.