Antimicrobial Resistance Situational Analysis 2019-2020: Design and Performance for Human Health Surveillance in Uganda.
Antimicrobial Resistance Situational Analysis 2019-2020: Design and Performance for Human Health Surveillance in Uganda.
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DOI：
10.3390/tropicalmed6040178
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发表时间：
2021-09-29
影响因子：
2.9
通讯作者：
Muwonge A
中科院分区：
文献类型：
--
作者：
Mugerwa I;Nabadda SN;Midega J;Guma C;Kalyesubula S;Muwonge A
人们对抗生素耐药性及其机制的了解已有六十多年了，但全球对其常规驱动因素进行描述的努力直到最近才获得动力。临床和社区耐药性的驱动因素不仅仅是临床实践，这就是为什么单一健康方法为控制抗生素耐药性提供了最现实的选择。值得注意的是，耐药性的出现是在环境中自然发生的，但与气候变化类似，目前的加速出现和传播带有拟人化影响的特征。如果不加以控制，这可能会破坏上个世纪的医学和农业进步。世卫组织建议各国制定、采用和实施跟踪抗生素耐药性水平变化趋势的战略，以解决这一问题。本文探讨了在乌干达制定和实施人类健康抗菌素耐药性监测战略的努力和进展。我们在2018年启动的应对抗菌素耐药性国家行动计划（AMR-NAP）的背景下这样做。我们讨论了在此框架下实施GLASS优先病原体监测的技术里程碑和进展。该框架的初步输出检查了性能，并比较了AMR和AMU监测数据，以解释观察到的趋势。我们的结论是，乌干达正在制定和实施一个有效的人类健康AMR监测战略取得进展。
Antibiotic resistance and its mechanisms have been known for over six decades, but global efforts to characterize its routine drivers have only gained momentum in the recent past. Drivers of clinical and community resistance go beyond just clinical practice, which is why one-health approaches offer the most realistic option for controlling antibiotic resistance. It is noteworthy that the emergence of resistance occurs naturally in the environment, but akin to climate change, the current accelerated emergence and spread bears hallmarks of anthropomorphic influence. If left unchecked, this can undo the medical and agricultural advancements of the last century. The WHO recommends that nations develop, adopt, and implement strategies that track the changing trends in antibiotic resistance levels to tackle this problem. This article examines efforts and progress in developing and implementing a human health antimicrobial resistance surveillance strategy in Uganda. We do so within the context of the National Action Plan for tackling antimicrobial resistance (AMR-NAP) launched in 2018. We discuss the technical milestones and progress in implementing surveillance of GLASS priority pathogens under this framework. The preliminary output of the framework examines the performance and compares AMR and AMU surveillance data to explain observed trends. We conclude that Uganda is making progress in developing and implementing a functional AMR surveillance strategy for human health.
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DOI：
10.4103/ijabmr.ijabmr_360_19
发表时间：
2020-07
影响因子：
1.1
作者：
Devi LS;Broor S;Rautela RS;Grover SS;Chakravarti A;Chattopadhya D
通讯作者：
Chattopadhya D
影响因子：
4.6
作者：
Di Gennaro, F.;Marotta, C.;Fantoni, M.
通讯作者：
Fantoni, M.
影响因子：
4.8
作者：
Pungcharoenkijkul, Supanun;Traipattanakul, Jantima;Santimaleeworagun, Wichai
通讯作者：
Santimaleeworagun, Wichai
影响因子：
2.8
作者：
Alhomoud F;Almahasnah R;Alhomoud FK
通讯作者：
Alhomoud FK
影响因子：
15.8
作者：
de Kraker ME;Stewardson AJ;Harbarth S
通讯作者：
Harbarth S