Prevalence of diabetes mellitus and prediabetes in the adult Romanian population: PREDATORR study
Prevalence of diabetes mellitus and prediabetes in the adult Romanian population: PREDATORR study
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DOI：
10.1111/1753-0407.12297
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发表时间：
2016-05-01
影响因子：
4.5
通讯作者：
Vlad, Adrian Radu
中科院分区：
文献类型：
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作者：
Mota, Maria;Popa, Simona Georgiana;Vlad, Adrian Radu
背景 PREDATORR（罗马尼亚糖尿病、糖尿病前期、超重、肥胖、血脂异常、高尿酸血症和慢性肾病的患病率）研究是第一项分析罗马尼亚 20-79 岁人群糖尿病 (DM) 和糖尿病前期患病率及其与心脏代谢、社会人口统计学和生活方式危险因素之间关系的全国性研究。分层、横断面、整群随机抽样设计。通过自填和访谈者填写的问卷收集社会人口统计学、生活方式和记忆数据，并进行生化分析和口服葡萄糖耐量测试。结果根据 2002 年罗马尼亚人口普查，随机选择了来自 101 个全科医生诊所的 2728 名参与者，概率与人口规模成正比。参与率为99.6%。 28.1% 的研究人群中发现血糖调节受损（前驱糖尿病、已知和未知 DM）。经年龄和性别调整后的 DM 总体患病率为 11.6% (95%CI 9.6%-13.6%)，其中 2.4% (95%CI 1.7%-3.1%) 患有未知 DM。 DM 患病率随着年龄的增长而增加，男性高于女性。经年龄和性别调整后的糖尿病前期患病率为 16.5%（95%CI 14.8%-18.2%），其中 60-79 岁年龄组和女性比例最高。肥胖、腹型肥胖、血脂异常、低教育水平和糖尿病家族史与葡萄糖代谢紊乱有关。结论 PREDATORR 研究显示，罗马尼亚成年人群中血糖调节受损的患病率很高，提供了有关 DM 和前驱糖尿病的患病率及其与多种危险因素之间关系的数据。
BackgroundThe PREDATORR (PREvalence of DiAbeTes mellitus, prediabetes, overweight, Obesity, dyslipidemia, hyperuricemia and chronic kidney disease in Romania) study is the first national study analyzing the prevalence of diabetes mellitus (DM) and prediabetes, and their association with cardiometabolic, sociodemographic, and lifestyle risk factors in the Romanian population aged 20-79 years.MethodsThis was an epidemiological study with a stratified, cross-sectional, cluster random sampling design. Sociodemographic, lifestyle, and anamnestic data were collected through self- and interviewer-administered questionnaires, and biochemical assays and oral glucose tolerance tests were performed.ResultsIn all, 2728 participants from 101 clinics of general practitioners were randomly selected, with a probability proportional to population size according to the 2002 Romanian Census. The participation rate was 99.6%. Impaired glucose regulation (prediabetes, known and unknown DM) was found in 28.1% of the study population. The overall age- and sex-adjusted prevalence of DM was 11.6% (95%CI 9.6%-13.6%), of which 2.4% (95%CI 1.7%-3.1%) had unknown DM. The prevalence of DM increased with age and was higher in men than in women. The age- and sex-adjusted prevalence of prediabetes was 16.5% (95%CI 14.8%-18.2%), with the highest percentage in the 60-79 year age group and in women. Obesity, abdominal obesity, dyslipidemia, low education level, and a family history of diabetes were associated with glucose metabolism disorders.ConclusionsThe PREDATORR study shows a high prevalence of impaired glucose regulation in the adult Romanian population, providing data on the prevalence of DM and prediabetes and their association with several risk factors.