Salmonellosis in cattle: Advantages of being an experimental model
Salmonellosis in cattle: Advantages of being an experimental model
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DOI：
10.1016/j.rvsc.2012.03.002
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发表时间：
2012-08-01
影响因子：
2.4
通讯作者：
Santos, Renato L.
中科院分区：
文献类型：
--
作者：
Costa, Luciana F.;Paixao, Tatiane A.;Santos, Renato L.
沙门氏菌病是一种重要的牛疾病，主要由鼠伤寒沙门氏菌和都柏林沙门氏菌引起。鼠伤寒沙门氏菌可引起小牛急性肠炎和渗出性腹泻。除了肠道疾病外，都柏林沙门氏菌还会引起全身感染，并可能导致怀孕奶牛流产。小牛被认为是人类非伤寒沙门氏菌病的相关模型。最近，小牛实验性口腔感染或回肠结扎接种已被广泛研究。本文综述了将牛沙门氏菌病作为一种自然疾病或动物模型的相关研究成果。(C)2012爱思唯尔有限公司。保留所有权利。
Salmonellosis is an important disease of cattle caused predominantly by Salmonella enterica serotypes Typhimurium (S. typhimurium) and Dublin (S. dublin). S. typhimurium causes acute enteritis and exudative diarrhea in calves. In addition to enteric disease, S. dublin can cause systemic infections, and may cause abortion in pregnant cows. Calves are considered a relevant model for non-typhoidal salmonellosis in humans. Experimental oral infections or inoculation of ligated ileal loops in calves have been extensively studied recently. This article reviews relevant published results regarding bovine salmonellosis as a natural disease or as an animal model. (C) 2012 Elsevier Ltd. All rights reserved.