Pectoralis and Rectus Abdominus Muscles for Potential Correction of Congenital Heart Defects
Pectoralis and Rectus Abdominus Muscles for Potential Correction of Congenital Heart Defects
复制标题
胸肌和腹直肌可潜在矫正先天性心脏缺陷
DOI：
10.1007/978-1-4613-8598-1_162
复制
发表时间：
1986
期刊：
影响因子：
--
通讯作者：
L. Stephenson
中科院分区：
文献类型：
--
作者：
T. Bitto;J. Mannion;R. Hammond;J. Macoviak;W. Rashkind;L. Edmunds;L. Stephenson
具有生长和分化潜力的收缩组织将成为疾病心肌的理想替代品，或作为发育不良的脑室的流出补片。我们用带蒂的横隔肌移植物替换了部分犬右心室，并证明了其长期存活[1]。连续刺激3个月后，当使用R波同步起搏器刺激时，肌肉移植物继续与心脏同步收缩。这些研究没有涉及骨骼肌贴片在血压产生中的作用。
Contractile tissue that has potential for growth and differentiation would serve as an ideal replacement for diseased myocardium or as an outflow patch for a hypoplastic ventricle. We have replaced portions of canine right ventricle with pedicled diaphragmatic muscle grafts and have demonstrated long-term survival [1]. After 3 months of continuous stimulation, the muscle grafts continued to contract in synchrony with the heart when stimulated with an R wave synchronous pacemaker. These studies did not address the contribution of the skeletal muscle patch in the generation of blood pressure.