Prevalence and Associated Factors of Bloating: Results From the Rome Foundation Global Epidemiology Study.
Prevalence and Associated Factors of Bloating: Results From the Rome Foundation Global Epidemiology Study.
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腹胀的患病率和相关因素：罗马基金会全球流行病学研究的结果。
DOI：
10.1053/j.gastro.2023.05.049
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发表时间：
2023
期刊：
影响因子：
29.4
通讯作者：
Lehmann,Marco
中科院分区：
文献类型：
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作者：
Ballou,Sarah;Singh,Prashant;Nee,Judy;Rangan,Vikram;Iturrino,Johanna;Geeganage,Grace;Löwe,Bernd;Bangdiwala,ShrikantI;Palsson,OlafurS;Sperber,AmiD;Lembo,Anthony;Lehmann,Marco
背景与目的腹胀是普通人群中的常见症状，也是肠脑相互作用障碍中的常见症状，尽管其发病率尚未得到很好的描述。本研究的目的是报告腹胀作为一种症状在全球人群中的流行情况，并在普通人群中确定与此症状相关的因素。方法对罗马基金会全球流行病学研究互联网调查数据进行分析。在排除了可能导致肠道症状的器质性原因的受访者后，目前的分析包括26个国家的51,425人。数据包括饮食、病史、生活质量和罗马四号诊断问题。出现腹胀的定义是在过去的3个月中每周至少有一次腹胀。描述性统计按国家、地区和肠脑相互作用诊断障碍估计患病率。Logistic回归分析了腹胀的预测因素。结果近18%的全球研究人群报告腹胀(从东亚的11%到拉丁美洲的20%不等)。患病率随着年龄的增长而下降，女性报告腹胀的可能性大约是男性的两倍。报告每周上腹痛(71.39%)、恶心(59.7%)或腹痛(61.69%)的受访者中，超过一半的人也报告每周至少一次腹胀。在Logistic回归分析中，腹痛(优势比为2.90)和上腹痛(优势比为2.07)的相关性最强。近18%的普通人群每周至少会出现一次腹胀。报告的腹胀患病率在年龄较大的人群中较低，在女性中最常见，并与腹痛密切相关。
Background & AimsBloating is a common symptom in the general population and among disorders of gut–brain interaction, although its prevalence has not been well characterized. The aim of this study was to report the prevalence of bloating as a symptom in the worldwide population and to identify factors associated with this symptom in the general population.MethodsRome Foundation Global Epidemiology Study internet survey data were analyzed. After excluding respondents with potential organic causes of bowel symptoms, the current analysis included 51,425 individuals in 26 countries. Data included diet, medical history, quality of life, and Rome IV diagnostic questions. Presence of bloating was defined as experiencing bloating at least once per week for the last 3 months. Descriptive statistics estimated prevalence by country, region, and disorder of gut–brain interaction diagnosis. Logistic regression evaluated predictors of bloating.ResultsNearly 18% of the global study population reported bloating (ranging from 11% in East Asia to 20% in Latin America). Prevalence decreased with age and women were approximately twice as likely as men to report bloating. More than one-half of respondents who reported weekly epigastric pain (71.39%), nausea (59.7%), or abdominal pain (61.69%) also reported bloating at least once per week. In logistic regression, the strongest associations were with abdominal pain (odds ratio, 2.90) and epigastric pain (odds ratio, 2.07).ConclusionsBloating is common throughout the world. Nearly 18% of the general population experience bloating at least once per week. Reported bloating prevalence is lower in older age groups, most common in women, and strongly associated with abdominal pain.