Susceptibility of Florida Aedes aegypti and Aedes albopictus to dengue viruses from Puerto Rico
Susceptibility of Florida Aedes aegypti and Aedes albopictus to dengue viruses from Puerto Rico
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DOI：
10.1111/jvec.12116
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发表时间：
2014-12-01
影响因子：
1.7
通讯作者：
Richards, Stephanie L.
中科院分区：
文献类型：
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作者：
Alto, Barry W.;Smartt, Chelsea T.;Richards, Stephanie L.
美国本土本地感染的登革热病例很罕见。然而，2009年、2010年和2013年佛罗里达州出现的登革热1型疫情，以及得克萨斯州出现的登革热1型和2型疫情表明存在传播的易感性。波多黎各与美国本土之间的旅行和商业往来很常见，这可能给输入性旅行者登革热病例带来风险。在佛罗里达州采集了蚊子，并用于评估它们对来自波多黎各的登革热病毒（DENV）的易感性。埃及伊蚊和白纹伊蚊易感染登革热1型和2型病毒。在埃及伊蚊和白纹伊蚊对登革热1型病毒的中肠感染率或扩散率方面未观察到显著差异（6 - 14%）。埃及伊蚊对登革热2型病毒的中肠感染率明显高于白纹伊蚊（埃及伊蚊约为28%；白纹伊蚊约为9%）。埃及伊蚊对登革热2型病毒的扩散率（23%）高于白纹伊蚊（0%），这表明白纹伊蚊不太可能是来自波多黎各的登革热2型分离株的重要传播媒介。结合佛罗里达州对登革热病毒传播的易感性对这些结果进行了讨论。
Locally acquired dengue cases in the continental U.S. are rare. However, outbreaks of dengue-1 during 2009, 2010, and 2013 in Florida and dengue-1 and -2 in Texas suggest vulnerability to transmission. Travel and commerce between Puerto Rico and the U.S. mainland is common, which may pose a risk for traveler-imported dengue cases. Mosquitoes were collected in Florida and used to evaluate their susceptibility to dengue viruses (DENV) from Puerto Rico. Aedes aegypti and Ae. albopictus were susceptible to virus infection with DENV-1 and -2. No significant differences were observed in rates of midgut infection or dissemination between Ae. aegypti or Ae. albopictus for DENV-1 (6-14%). Aedes aegypti was significantly more susceptible to midgut infection with DENV-2 than Ae. albopictus (Ae. aegypti, approximate to 28%; Ae. albopictus, approximate to 9%). The dissemination rate with dengue-2 virus for Ae. aegypti (23%) was greater than Ae. albopictus (0%), suggesting that Ae. albopictus is not likely to be an important transmitter of the DENV-2 isolate from Puerto Rico. These results are discussed in light of Florida's vulnerability to DENV transmission.