DNA sequence of the transfer RNA region of bacteriophage T4: implications for transfer RNA synthesis.
DNA sequence of the transfer RNA region of bacteriophage T4: implications for transfer RNA synthesis.
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噬菌体 T4 转移 RNA 区域的 DNA 序列：对转移 RNA 合成的影响。
DOI：
10.1073/pnas.78.2.889
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发表时间：
1981
影响因子：
11.1
通讯作者：
McClain,WH
中科院分区：
文献类型：
--
作者：
Mazzara,GP;Plunkett3rd,G;McClain,WH
编码噬菌体T4的8个trna和2个稳定rna的序列在T4基因组上分成两个簇，间隔约500个碱基对。确定了部分区域的DNA序列。在每个聚类中，编码序列只被一个或几个碱基对分开。这些发现表明，rna可能是由单一的多聚体转录产物加工而成的，最初的核内裂解产生了先前描述的单体和二聚体前体。
Sequences encoding eight tRNAs and two stable RNAs of bacteriophage T4 are grouped together on the T4 genome in two clusters, separated by approximately 500 base pairs. The DNA sequence of part of this region was determined. Within each cluster coding sequences are separated by only one or a few base pairs. These findings imply that the RNAs may be processed from a single multimeric transcript, with initial endonucleolytic cleavages generating the previously characterized monomeric and dimeric precursors.