Examination of Mechanical Properties and Photoelastic Properties of Gel Material for Blood Vessel Mimics
Examination of Mechanical Properties and Photoelastic Properties of Gel Material for Blood Vessel Mimics
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血管模拟物凝胶材料的机械性能和光弹性性能检查
DOI：
10.1115/1.4051516
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
S. Hata
中科院分区：
文献类型：
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作者：
D. Yamada;S. Hori;S. Abe;Y. Kumeno;T. Yamazaki;C. Oka;J. Sakurai;S. Hata
导管手术是一种微创治疗，其中视觉信息仅限于由X射线相机生成的二维图像。这导致由导管施加到血管壁上的应力损坏血管的可能性。因此，医生必须熟练掌握导管手术。我们提出了一个导管手术模拟器，可视化的压力施加到血管壁使用光弹性。该模拟器的制造需要创建使用光弹性再现血管组织的物理特性的血管模拟物。本研究探讨了凝胶材料的力学和光弹性性能，并选择了一种适合于制作血管模拟物的凝胶组合物。通过改变组成比，聚乙烯醇（PVA）水凝胶的力学性能在70-335 kPa范围内变化，双网络（DN）水凝胶的力学性能在0.13-1.06 MPa范围内变化。这些凝胶可以通过改变材料组成来调节，以提供与血管相似的杨氏模量。通过改变组成比，PVA水凝胶的光弹性性质在1.38-2.76 × 10 - 9/Pa的范围内变化，而DN凝胶通过改变组成比在0.012-0.029 × 10 - 9/Pa的范围内变化。
Catheter surgery is a minimally invasive treatment in which visual information is limited to a two-dimensional image generated by an X-ray camera. This results in the possibility that stress applied by the catheter onto a blood vessel wall damages the vessel. Doctors must therefore be skillful at catheter surgery. We proposed a catheter surgery simulator that visualizes the stress applied to the blood vessel wall using photoelasticity. The manufacture of this simulator requires creating blood vessel mimics that reproduce the physical properties of blood vessel tissue using photoelasticity. This study investigated the mechanical and photoelastic properties of gel materials and selected a gel composition suitable for making blood vessel mimics. The mechanical properties of polyvinyl alcohol (PVA) hydrogel changed in the range 70–335 kPa by changing the composition ratio, and double network (DN) gel changed in the range 0.13–1.06 MPa by changing the composition ratio. These gels could be adjusted by changing the material composition to provide Young's moduli similar to that of blood vessels. The photoelastic properties of PVA hydrogel changed in the range 1.38–2.76 × 10−9/Pa by changing the composition ratio, and DN gel changed in the range 0.012–0.029 × 10−9/Pa by changing the composition ratio.