Influence of oleic acid on the structure of a mixture of hydrated model stratum corneum fatty acids and their soaps
Influence of oleic acid on the structure of a mixture of hydrated model stratum corneum fatty acids and their soaps
复制标题
油酸对水合模型角质层脂肪酸及其皂混合物结构的影响
DOI：
10.1016/0927-7757(94)02919-9
复制
发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Geoffrey Lee
中科院分区：
文献类型：
--
作者：
R. Lieckfeldt;J. Villalaín;J. Gomez;Geoffrey Lee
已检查饱和和不饱和脂肪酸及其皂的水合（32%（w/w）水）混合物的相行为。通过逐渐增加油酸的比例，可以表明这种不饱和组分部分地作为单独的相存在于其它组分中。不饱和脂肪酸在25°C下形成III相，而饱和脂肪酸在所采用的条件下形成脂肪酸-皂晶体。这些结果有助于解释人体角质层脂质组分中脂肪酸（以及胆固醇）所起的作用。本研究的一个特点是通过X-射线衍射，差示扫描量热法和傅里叶变换红外光谱得到的结果进行比较。
The phase behaviour of a hydrated (32% (w/w) water) mixture of saturated and unsaturated fatty acids and their soaps has been examined. By progressively increasing the proportion of oleic acid, it could be shown that this unsaturated component exists partly as a separate phase within the others. The unsaturated fatty acids form an HIIphase at 25°C, whereas the saturated fatty acids form a fatty acid—soap crystal under the conditions employed. The results help to explain the role played by the fatty acids (and also cholesterol) within the lipid fraction of human stratum corneum. A feature of this study is a comparison of the results obtained by X-ray diffraction, differential scanning calorimetry and Fourier transform infrared spectroscopy.
影响因子：
2.9
作者：
CISTOLA, DP;ATKINSON, D;SMALL, DM
通讯作者：
SMALL, DM