Global Burden of Oral Conditions in 1990-2010: A Systematic Analysis
Global Burden of Oral Conditions in 1990-2010: A Systematic Analysis
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DOI：
10.1177/0022034513490168
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发表时间：
2013-07-01
影响因子：
7.6
通讯作者：
Murray, C. J. L.
中科院分区：
文献类型：
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作者：
Marcenes, W.;Kassebaum, N. J.;Murray, C. J. L.
2010年全球疾病负担（GBD）研究对1990年、2005年和2010年291种疾病和伤害的负担进行了可比估计。本文报告了2010年未经治疗的龋齿、严重牙周炎和严重牙齿脱落的全球负担，并将这些数字与1990年的新估计数字进行了比较。我们使用残疾调整生命年（DALYs）和残疾生活年（YLDs）指标来量化负担。口腔疾病影响了39亿人，在整个GBD 2010研究中，未经治疗的恒牙龋齿是评估的最普遍的疾病（所有年龄段的全球患病率为35%）。口腔疾病合计占全球1500万伤残调整生命年（占所有伤残调整生命年的1.9%；占所有伤残调整生命年的0.6%），意味着每10万人平均健康损失224岁。1990年至2010年间，由于口腔疾病导致的伤残调整生命年增加了20.8%，主要原因是人口增长和老龄化。严重牙周炎和未经治疗的龋齿导致的伤残调整生命年增加，而严重牙齿脱落导致的伤残调整生命年减少。残疾调整寿命因年龄组和地区而异，但因性别而异。研究结果突出了应对世界各地，特别是发展中社区紧迫口腔卫生需求的多样性所面临的挑战。
The Global Burden of Disease (GBD) 2010 Study produced comparable estimates of the burden of 291 diseases and injuries in 1990, 2005, and 2010. This article reports on the global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 and compares those figures with new estimates for 1990. We used disability-adjusted life-years (DALYs) and years lived with disability (YLDs) metrics to quantify burden. Oral conditions affected 3.9 billion people, and untreated caries in permanent teeth was the most prevalent condition evaluated for the entire GBD 2010 Study (global prevalence of 35% for all ages combined). Oral conditions combined accounted for 15 million DALYs globally (1.9% of all YLDs; 0.6% of all DALYs), implying an average health loss of 224 years per 100,000 population. DALYs due to oral conditions increased 20.8% between 1990 and 2010, mainly due to population growth and aging. While DALYs due to severe periodontitis and untreated caries increased, those due to severe tooth loss decreased. DALYs differed by age groups and regions, but not by genders. The findings highlight the challenge in responding to the diversity of urgent oral health needs worldwide, particularly in developing communities.