Reduced cognitive control of a visually bistable image in schizophrenia.
Reduced cognitive control of a visually bistable image in schizophrenia.
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精神分裂症患者对视觉双稳态图像的认知控制减少。
DOI：
10.1017/s1355617711000245
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Chen,Yue
中科院分区：
文献类型：
--
作者：
McBain,Ryan;Norton,DanielJ;Kim,Jejoong;Chen,Yue
精神分裂症与无法控制和协调思想、行为和感知有关。在传统的认知控制评估中，刺激的多个感觉特征被同时操纵，引入了自下而上的感知信息的混杂作用。为了克服这一困难，我们使用了一种模糊的视觉刺激(Necker Cube)，它允许通过持续的感觉输入来测量认知控制。受试者(20名患者和20名对照组)被要求控制他们对透明内克立方体的感知，方法是在刺激的前面或后面保持一个指定的平面，其位置在感知上是双稳的。患者在控制他们对立方体的感知方面存在严重缺陷。当系统地操纵视觉特征(指定的立方体平面和其他平面之间的亮度对比度)时，发现了一种相互作用，精神分裂症患者在最高对比度条件下不再表现不佳。这些结果显示了患者在没有视觉调制的情况下控制知觉的障碍，并表明基于知觉的方法在精神分裂症认知补救中的潜在效用。(JINS，2011,551-556)
Schizophrenia is associated with the inability to control and coordinate thoughts, actions, and perceptions. In conventional assessments of cognitive control, multiple sensory features of stimuli are concomitantly manipulated, introducing a confounding role of bottom-up perceptual information. To overcome this difficulty, we used an ambiguous visual stimulus (Necker cube), which allowed measurement of cognitive control with constant sensory input. Subjects (20 patients, 20 controls) were asked to control their perception of a transparent Necker cube by keeping a designated plane at the front or back of the stimulus, the position of which is perceptually bistable. Patients were highly deficient at controlling their perception of the cube. When a visual feature (the luminance contrast between a designated cube plane and the other planes) was systematically manipulated, an interaction was found whereby schizophrenia patients no longer under-performed on the highest contrast condition. These results show patients’ impairment of controlling perception in the absence of visual modulation and suggest the potential utility of perceptually based approaches to cognitive remediation in schizophrenia. (JINS, 2011, 551–556)