Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries
Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries
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DOI：
10.1016/j.jdent.2010.05.004
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发表时间：
2010-08-01
影响因子：
4.4
通讯作者：
Sumi, Yasunori
中科院分区：
文献类型：
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作者：
Shimada, Yasushi;Sadr, Alireza;Sumi, Yasunori
目的：在这项实验室研究中，我们研究了使用扫频源光学相干断层扫描（SS-OCT）作为一种诊断工具为occlusal carries.Methods：一百一十一调查网站的咬合裂缝被选中从62个提取的牙齿和视觉检查使用传统的牙科设备，没有任何放大。在与进行常规检查的位置相同的位置进行了SS-OCT观察。然后使用金刚石锯将牙齿切片，并在共聚焦激光扫描显微镜（CLSM）下直接观察。在每次观察中对龋齿的存在和程度进行评分，并将从SS-OCT和常规目视检查获得的结果与CLSM进行比较。计算SS-OCT的重复性、敏感性和特异性指数，并与目视检查进行比较。结果：SS-OCT能够在基于背向散射信号合成的断层图像中清晰地检测出釉质脱矿病变（灵敏度= 0.98）。虽然SS-OCT对牙本质龋的敏感性高于目视检查，但检测水平下降至0.60。与激光共聚焦显微镜相比，SS-OCT的诊断准确性优于常规目视检查（肉眼检查和SS-OCT的Az值，釉质脱矿为0.74 vs 0.86，牙本质龋为0.68 vs 0.80;斯皮尔曼相关系数与CLSM;肉眼检查：0.665，SS-OCT：0.824）。龋性脱矿，特别是在釉质，可以清楚地区分为一个突出的区域，由于散射光匹配的脱矿区的位置在裂缝的基础和相关性良好的结果与CLSM。(C)2010爱思唯尔有限公司保留所有权利。
Objectives: In this laboratory study, we examined the use of a swept-source optical coherence tomography (SS-OCT) as a diagnostic tool for occlusal caries.Methods: One-hundred and eleven investigation sites of occlusal fissures were selected from 62 extracted teeth and examined visually using conventional dental equipment without any magnification. SS-OCT observations were carried out on the same locations as where the conventional examination had been performed. The teeth were then sectioned using a diamond saw and directly viewed under a confocal laser scanning microscope (CLSM). Presence and extent of caries was scored in each observation and the obtained results from SS-OCT and conventional visual inspection were compared with the CLSM. The reproducibility and indices of sensitivity and specificity of SS-OCT were calculated and compared with those of the visual inspection. The results were statistically analyzed using receiver operating characteristic (ROC) curve and Spearman rank correlation test.Results: SS-OCT could clearly detect the presence of enamel demineralization lesion in a tomography image synthesized based on the backscatter signal (sensitivity = 0.98). Although the sensitivity for dentine caries of SS-OCT was over that of the visual inspection, the detection level was decreased to 0.60. When the methods were compared to the CLSM, the diagnostic accuracy of SS-OCT was better than that of the conventional visual inspection (Az values of visual inspection and SS-OCT, 0.74 versus 0.86 for enamel demineralization, 0.68 versus 0.80 for dentine caries; Spearman's correlation coefficients to CLSM; visual inspection: 0.665, SS-OCT: 0.824).Conclusions: The carious demineralization, especially in enamel, can be clearly discriminated as a highlighted area due to scattering of light matches the location of demineralized area at the base of the fissure and the results correlated well with the CLSM. (C) 2010 Elsevier Ltd. All rights reserved.