Characteristics of spontaneous eyeblink activity during video display terminal use in healthy volunteers
Characteristics of spontaneous eyeblink activity during video display terminal use in healthy volunteers
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DOI：
10.1007/s00417-003-0786-6
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发表时间：
2003-11-01
影响因子：
2.7
通讯作者：
Schlote, T
中科院分区：
文献类型：
--
作者：
Freudenthaler, N;Neuf, H;Schlote, T
目的.分析正常志愿者使用视屏显示终端（VDT）前和视屏显示终端时的自发眨眼率（SEBR）和眨眼间隔（IEBI）。方法.用计算机视频分析系统对51名正常志愿者的SEBR进行了测量。只有完整的眨眼记录在10分钟内在三种不同的条件下：在谈话期间，在VDT使用无角膜麻醉，并在VDT使用角膜麻醉。测定IEBI（以秒计）以研究SEBR的个体时间依赖性变化。结果与会话期间的SEBR（平均15.54次眨眼/分钟，标准差+/-13.74次眨眼/分钟）相比，在没有角膜麻醉的情况下使用VDT期间的SEBR显著降低（5.34 +/-4.53次眨眼/分钟）。角膜麻醉进一步显著降低SEBR（2.78 +/- 2.77次眨眼/min）。SEBR的特点是显着的个体间变异，范围在11和664眨眼/10分钟之间的谈话，4和189眨眼之间的VDT使用无角膜麻醉和1和119眨眼之间的VDT使用角膜麻醉。SEBR（在谈话期间或在VDT使用期间）和泪膜的质量（破裂时间）或数量（Schirmer I试验，Jones试验）之间没有显著相关性。IEBI的评价显示三种不同类型的眨眼模式在VDT使用无角膜麻醉。1型的特征在于非常低的SEBR（0-2次眨眼/min）和相对均匀的眨眼分布，2型显示中等SEBR（1.2-8.5次眨眼/min），包括另外三种亚型。3型的特征在于规则或不规则模式的高SEBR（6.8-18.9次眨眼/分钟）。结论. VDT的使用与健康受试者SEBR的显著降低相关。SEBR存在明显的个体间差异，SEBR与正常眼泪膜参数无相关性。SEBR通过角膜麻醉进一步降低。不同的眨眼模式的存在可能与各种外源性和内源性因素有关，并可能导致更好地了解VDT使用过程中的眼部反应。
Purpose. To analyse the spontaneous eyeblink rate (SEBR) and inter-eyeblink intervals (IEBI) of normal volunteers before and during video display terminal (VDT) use. Methods. The SEBR of 51 normal volunteers was measured by counting the absence of the corneal reflex using a computer-based video analysis system. Only complete eyeblinks were recorded within 10 min under three different conditions: during a conversation, during VDT use without corneal anaesthesia, and during VDT use with corneal anaesthesia. The IEBI (in seconds) were determined to study individual time-dependent changes of SEBR. Results. In comparison with SEBR during conversation (mean 15.54 eyeblinks/min, standard deviation +/-13.74 eyeblinks/min) the SEBR decreased significantly during VDT use without corneal anaesthesia (5.34 +/- 4.53 eyeblinks/min). Corneal anaesthesia further significantly reduced SEBR (2.78 +/- 2.77 eyeblinks/min). The SEBR was characterized by marked interindividual variability, ranging between 11 and 664 eyeblinks/10 min during conversation, between 4 and 189 eyeblinks during VDT use without corneal anaesthesia and between 1 and 119 eyeblinks at VDT use with corneal anaesthesia. No significant correlation between SEBR (during conversation or during VDT use) and quality (break-up time) or quantity (Schirmer I test, Jones test) of the tear film could be detected. Evaluation of the IEBI revealed three different types of eyeblink pattern during VDT use without corneal anaesthesia. Type 1 was characterized by a very low SEBR (0-2 eyeblinks/min) and relatively homogeneous distribution of eyeblinks, type 2 showed a moderate SEBR (1.2-8.5 eyeblinks/min) including three further subtypes. Type 3 was characterized by a high SEBR (6.8-18.9 eyeblinks/min) of regular or irregular pattern. Conclusions. VDT use is associated with a profound decrease of the SEBR in healthy subjects. There are marked interindividual differences in SEBR and no correlation between the SEBR and ocular tear film parameters in normal eyes. The SEBR is further reduced by corneal anaesthesia. The presence of different patterns of eyeblinking may be related to various exogenous and endogenous factors and may lead to a better understanding of ocular reactions during VDT use.