Peptides. VI. Some Oxime Carbonates as Novel t-Butoxycarbonylating Reagents

Peptides. VI. Some Oxime Carbonates as Novel t-Butoxycarbonylating Reagents
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肽。

DOI:
10.1246/bcsj.50.718
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发表时间:
1977
影响因子:
4
通讯作者:
Kamiya Takashi
Kamiya Takashi
中科院分区:
化学3区
文献类型:
--
作者:
M. Itoh;D. Hagiwara;Kamiya Takashi

文献摘要

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通过肟氯甲酸酯合成了肟的叔丁氧羰基衍生物。其中,(叔丁氧基羰基氧基亚氨基)丙二酸二乙酯和2-(叔丁氧基羰基氧基亚氨基)-2-苯乙腈用于在各种条件下制备叔丁氧基羰基氨基酸。结果汇总于表中。
Several t-butoxycarbonyl derivatives of oximes were prepared through the corresponding oxime chloroformates. Of these, diethyl (t-butoxycarbonyloxyimino)malonate and 2-(t-butoxycarbonyloxyimino)-2-phenylacetonitrile were utilized for the preparation of t-butoxycarbonylamino acids under various conditions. The results are summarized in a table.