ON AND OFF COMPONENTS IN AUDITORY EVOKED-POTENTIAL
ON AND OFF COMPONENTS IN AUDITORY EVOKED-POTENTIAL
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DOI：
10.3758/bf03199736
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发表时间：
1978-01-01
期刊：
影响因子：
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通讯作者：
PICTON, TW
中科院分区：
文献类型：
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作者：
HILLYARD, SA;PICTON, TW
人类听觉诱发电位（AEP）的ON和OFF分量可能由独立的生理机制介导。对简短音调的响应显然由重叠的“开”和“关”响应组成。进行了两个实验来评估这些建议。首先，AEP 被记录为以固定速率呈现的不同持续时间的突发音调。随着突发音调变长，它们会引起较小的 ON 响应和较大的 OFF 响应，特别是当任一响应跟随另一个响应的时间小于 5 秒时。显然，ON 和 OFF 反应在生理上并不是独立的。其次，将 25 ms 音调的 AEP 与 2000 ms 音调的 ON 响应进行比较。在刺激间隔为 4 s 时，前者减去后者的 AEP 形成的差值波包含明显的 N1（约 100 ms）和 P2（约 180 ms）分量，这些分量以前被解释为 OFF 响应。差异波中的这些分量在 10 秒刺激间隔时大大减少甚至反转，其中对连续刺激的 ON 和 OFF 响应之间的相互作用被最小化。 AEP 中对短暂音调的任何残余关闭响应（如果存在）其幅度都非常小。
The ON and OFF components of the human auditory evoked potential (AEP) may be mediated by independent physiological mechanisms. The response to a brief tone apparently consists of overlapping ON and OFF responses. Two experiments were performed to evaluate these proposals. First, AEP were recorded to tone bursts of various durations presented at a fixed rate. As the tone bursts were made longer, they evoked smaller ON responses and larger OFF responses, particularly when either response followed the other by less than 5 s. Evidently, ON and OFF responses are not physiologically independent. Second, the AEP to a 25 ms tone was compared with the ON response to a 2000 ms tone. At an interstimulus interval of 4 s, the difference wave formed by subtracting the latter AEP from the former contained clear N1 (about 100 ms) and P2 (about 180 ms) components, which previously have been interpreted as an OFF response. These components in the difference wave were greatly reduced or even inverted at 10 s interstimulus intervals, where interactions between ON and OFF responses to successive stimuli were minimized. Any residual OFF response in the AEP to a brief tone is very small in amplitude, if present at all.